Home Drug Codes J Codes J1956 · LEVOFLOXACIN
Updated July 1st, 2026

LEVOFLOXACIN J Code: J1956

Injection, levofloxacin, 250 mg

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Q4 2026 Medicare Payment Limit for J1956, effective October 1, 2026: $2.565 per HCPCS billing unit, up 34.4% from $1.909. From CMS's final file.

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Medicare Payment Limit ?
$1.909
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
26
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Drug & Product Overview

HCPCS Descriptor Injection, levofloxacin, 250 mg
HCPCS Added Date January 1, 1999
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection | Injection, Solution | Not Available

About LEVOFLOXACIN

Levofloxacin is a medication aligned to the HCPCS J Code: J1956 for billing, pricing, and reimbursement purposes in the United States. This Antibiotic medication is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to treat a variety of bacterial infections. Levofloxacin belongs to a class of drugs known as quinolone antibiotics. It works by stopping the growth of bacteria. Levofloxacin injection is used if you cannot take the medication by mouth.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 26 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00143-9315-24 Levofloxacin Hikma Pharmaceuticals USA Inc. 24 250 MG / 50 ML
00409-2220-24 Levofloxacin Hospira, Inc 24 250 MG / 50 ML
25021-0132-81 Levofloxacin Sagent Pharmaceuticals 24 250 MG / 50 ML
44567-0435-24 Levofloxacin WG Critical Care, LLC 24 250 MG / 50 ML
63323-0355-50 Levofloxacin Fresenius Kabi USA, LLC 24 250 MG / 50 ML
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LEVOFLOXACIN
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LEVOFLOXACIN Pricing & Reimbursement

J1956 Private Payer Reimbursement
$2.22 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

LEVOFLOXACIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Levofloxacin (J1956) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

LEVOFLOXACIN Medically Unlikely Edits (MUE)

The most billing units of J1956 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 250 mg.

Practitioner Office & Hospital Outpatient
4 units / day
= 1,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

LEVOFLOXACIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Bacterial Exacerbation of Chronic Bronchitis Acute Bacterial Sinusitis Acute Pyelonephritis Chronic Bacterial Prostatitis Community-Acquired Pneumonia Complicated Skin and Skin Structure Infections Complicated Urinary Tract Infection Complicated Urinary Tract Infection or Acute Pyelonephritis Complicated Urinary Tract Infections or Acute Pyelonephritis Inhalational Anthrax (Post-Exposure) Nosocomial Pneumonia Plague Uncomplicated Skin and Skin Structure Infections Uncomplicated Urinary Tract Infection Uncomplicated Urinary Tract Infections

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Frequently Asked Questions

Is there an available Levofloxacin billing and coding guide?
We have not yet identified a manufacturer source of Levofloxacin billing and coding information.
Are there any available Levofloxacin patient assistance programs?
Our team did not identify a source for Levofloxacin patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Levofloxacin prescribing information?
LEVOFLOXACIN prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Levofloxacin side effect information?
Our team has not yet identified a source of side effects information for LEVOFLOXACIN. Please check back in a few weeks.
Does billing LEVOFLOXACIN require JZ/JW wastage modifiers?
CMS has identified LEVOFLOXACIN(J1956) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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