Home › Drug Codes › J Codes › J0278 · AMIKACIN SULFATE
Updated July 1st, 2026

AMIKACIN SULFATE J Code: J0278

Injection, amikacin sulfate, 100 mg

Login to unlock all benchmarks

Q4 2026 Medicare Payment Limit for J0278, effective October 1, 2026: $0.612 per HCPCS billing unit, down 0.3% from $0.614. From CMS's final file.

?
Medicare Payment Limit ?
$0.614
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
Login to view
WAC · AWP ?
$•••.••
Login to view
NDCs Crosswalked ?
17
View NDC crosswalk →

Drug & Product Overview

HCPCS Descriptor Injection, amikacin sulfate, 100 mg
HCPCS Added Date January 1, 2006
Manufacturer Multiple Manufacturers
Route of Administration Intramuscular, Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection | Injection, Solution

About AMIKACIN SULFATE

Amikacin Sulfate is a medication aligned to the HCPCS J Code: J0278 for billing, pricing, and reimbursement purposes in the United States. Classified under Antibiotic, it is administered via the intramuscular or intravenous routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to prevent or treat a wide variety of bacterial infections. Amikacin belongs to a class of drugs known as aminoglycoside antibiotics. It works by stopping the growth of bacteria.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 17 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00641-6166-10 Amikacin Sulfate Hikma Pharmaceuticals USA Inc. 100 1000 MG / 4 ML
23155-0290-41 Amikacin Sulfate Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 50 500 MG / 2 ML
25021-0173-02 amikacin sulfate Sagent Pharmaceuticals 50 500 MG / 2 ML
63323-0815-02 Amikacin Sulfate Fresenius Kabi USA, LLC 50 500 MG / 2 ML
83301-0022-02 Amikacin Sulfate Mullan Pharmaceutical Inc. 50 500 MG / 2 ML
•••••-••••-•• Log in to view AMIKACIN SULFATE
AMIKACIN SULFATE
AMIKACIN SULFATE
Login to view 12 more NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.
Login →

AMIKACIN SULFATE Pricing & Reimbursement

J0278 Private Payer Reimbursement
$0.85 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

AMIKACIN SULFATE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96372 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular Login for More
Not on the CMS JW / JZ list

CMS does not include Amikacin Sulfate (J0278) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0278. Wastage billing guide →

AMIKACIN SULFATE Medically Unlikely Edits (MUE)

The most billing units of J0278 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 100 mg.

Practitioner Office & Hospital Outpatient
15 units / day
= 1,500 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

AMIKACIN SULFATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Serious infections due to susceptible Gram-negative bacteria Serious infections due to susceptible strains of Gram-negative bacteria Uncomplicated urinary tract infections
Drug Class
Aminoglycoside Antibacterial [EPC]Aminoglycosides [CS]

Login for BuyandBill.com Analytics

Unlock deeper insights with BuyandBill’s Comparative Report!

  • Compare ASP, WAC, and AWP across drugs.
  • Visualize Drug Price Movement Over Time
  • Tailor reports to drug class, manufacturer, or HCPCS Code.
  • Compare Biosimilar and 505(b)(2) products.
Access Full Report →

Frequently Asked Questions

Is there an available Amikacin Sulfate billing and coding guide?
We have not yet identified a manufacturer source of Amikacin Sulfate billing and coding information.
Are there any available Amikacin Sulfate patient assistance programs?
Our team did not identify a source for Amikacin Sulfate patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Amikacin Sulfate prescribing information?
AMIKACIN SULFATE prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Amikacin Sulfate side effect information?
Our team has not yet identified a source of side effects information for AMIKACIN SULFATE. Please check back in a few weeks.
Does billing AMIKACIN SULFATE require JZ/JW wastage modifiers?
CMS does not include AMIKACIN SULFATE (J0278) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0278. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.

Related Drug Codes

Explore billing, coding, and pricing for drugs related to AMIKACIN SULFATE.

J1956LEVOFLOXACINInjection, levofloxacin, 250 mgMultiple ManufacturersAdded January 1, 1999J1580GENTAMICIN SULFATEInjection, garamycin, gentamicin, up to 80 mgMultiple ManufacturersAdded January 1, 1984J3260TOBRAMYCIN SULFATEInjection, tobramycin sulfate, up to 80 mgMultiple ManufacturersAdded January 1, 1982J7682BETHKISTobramycin, inhalation solution, fda-approved final product, non-compounded, unit dose form, administered through dme, per 300 milligramsMultiple ManufacturersAdded January 1, 2000C9462BAXDELAInjection, delafloxacin, 1 mgMelinta TherapeuticsAdded April 1, 2018J0120TETRACYCLINE HCLInjection, tetracycline, up to 250 mgMultiple ManufacturersAdded January 1, 1986J0121NUZYRAInjection, omadacycline, 1 mgParatek PharmaceuticalsAdded October 1, 2019J0122XERAVAInjection, eravacycline, 1 mgTetraphase PharmaceuticalsAdded October 1, 2019J0200ALATROFLOXACIN MESYLATEInjection, alatrofloxacin mesylate, 100 mgAdded January 1, 2000J0290AmpicillinInjection, ampicillin sodium, 500 mgMultiple ManufacturersAdded January 1, 1984