CPT Administration Code: 96366 | Intravenous Infusion

Code Overview

CPT® administration code details for 96366.

CPT Code Descriptor Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Code Category Intravenous Infusion

Route / Technique Intravenous Infusion

Code Type Add-on Code

About Intravenous Infusion – 96366

CPT 96366 is an add-on code reported for each additional hour of therapeutic, prophylactic, or diagnostic intravenous infusion beyond the initial hour described by the primary infusion code. It applies when the same infused substance or drug is continued sequentially beyond the first hour, and it must always be billed alongside a qualifying initial IV infusion service. This code captures incremental infusion time and is not reported as a stand-alone service.

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96366 RVU Breakdown & Medicare Reimbursement

Based on the CY 2026 CMS Physician Fee Schedule. National payment amounts, before geographic (GPCI) adjustment.

Component	Facility	Non-Facility
Work RVU — physician work	0.18	0.18
Practice Expense RVU — staff, supplies, equipment	0.45	0.45
Malpractice RVU — professional liability	0.01	0.01
Total RVUs	0.64	0.64
Medicare Payment — Total RVUs × $33.4009 CF	$21.38	$21.38

CY 2026 Medicare Conversion Factor: $33.4009. Facility and non-facility practice-expense RVUs are equal for this code.

96366 Locality-Adjusted Rates

Medicare payment varies by locality via GPCI adjustment. Log in to view rates for all 100+ Medicare localities.

Medicare Locality	Facility	Non-Facility
National (unadjusted)	$21.38	$21.38
Los Angeles–Long Beach, CA
Manhattan, NY
Houston, TX
Miami, FL

Related Administration Codes

The therapeutic IV-infusion code family. Report one initial code per encounter; add-on codes are listed separately in addition to the primary procedure.

CPT Code	Description	Type
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour	Initial
96366This page	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)	Add-on
96367	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); additional sequential infusion of a new drug/substance, up to 1 hour (List separately in addition to code for primary procedure)	Add-on
96368	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); concurrent infusion (List separately in addition to code for primary procedure)	Add-on

Drugs Commonly Billed with 96366

HCPCS-coded drugs frequently administered under this CPT code. The list below is not exhaustive.

HCPCS Code	Drug	HCPCS Descriptor
J3262	ACTEMRA	Injection, tocilizumab, 1 mg
J0885	EPOGEN	Injection, epoetin alfa, (for non-esrd use), 1000 units
J1299	SOLIRIS	Injection, eculizumab, 2 mg
J3358	STELARA	Ustekinumab, for intravenous injection, 1 mg
J0130	ABCIXIMAB	Injection abciximab, 10 mg

Frequently Asked Questions

What are CPT Administration Codes?

CPT administration codes cover the work of giving a drug to a patient, such as an injection or an infusion. The drug itself is billed with its HCPCS J-code, and the administration is billed with a CPT code. Both go on the same claim. Learn More →

What is the Medicare Conversion Factor?

The conversion factor is the dollar amount CMS uses to turn a code's total RVUs into a Medicare payment. This page uses the CY 2026 conversion factor of $33.4009. CMS updates it every year in the Physician Fee Schedule final rule.

Facility vs. Non-Facility?

The non-facility rate applies in a physician office, where the practice pays for its own staff, supplies, and equipment, so the rate is usually higher. The facility rate applies in hospital outpatient departments and ASCs, where the facility bills for those costs separately.

How do I decide which administration code to use?

Pick the code that matches the type of drug, the route, and how long the administration takes. Start from the highest-ranking service you performed, then add the appropriate add-on codes for extra time or extra drugs. Manufacturer billing and coding guides often list suggested administration codes.

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CPT Administration Code: 96366 – Intravenous Infusion