Billing Drug Wastage: JZ and JW

Reporting discarded amounts on Medicare Part B single-dose drugs

Medicare Part B
Modifiers
JZ · JW
Single-dose codes
435
Last updated
September 6, 2026
Source
CMS

The basics

Why drug wastage gets reported

When a Medicare Part B patient receives a drug from a single-dose container, Medicare pays for both the administered and the discarded amounts. Under the Infrastructure Investment and Jobs Act (IIJA), manufacturers must refund CMS for discarded amounts that exceed 10% of total drug charges per quarter, so accurate wastage reporting matters.

A refundable drug is a single-source or biosimilar product that is:

  • Separately payable under Medicare Part B,
  • Supplied in a single-dose container or single-use package, and
  • Associated only with NDCs labeled as single-dose or single-use.

The two modifiers

JW and JZ at a glance

When billing Medicare Part B for separately payable drugs from single-dose or single-use containers, providers must report wastage with one of two HCPCS modifiers.

JW

Discarded amount

Reports the amount of a drug discarded from a single-dose container. The wasted units are billed on their own claim line so Medicare reimburses the discarded amount.

JZ

No waste

Attests that no drug was discarded from a single-dose container. Use of the JZ modifier is mandatory whenever there is no wastage to report.

The full list

CMS single-dose & single-use HCPCS codes

On the CMS-1500 claim form, the JW and JZ modifiers are entered in box 24(D), adjacent to the corresponding HCPCS code. The codes below identify drugs CMS lists as supplied in single-dose or single-use packaging.

HCPCSDescriptor
J0121Injection, omadacycline, 1 mg
J0122Injection, eravacycline, 1 mg
J0135Injection, adalimumab, 20 mg
J0172Injection, aducanumab-avwa, 2 mg
J0174Injection, lecanemab-irmb, 1 mg
J0177Injection, aflibercept HD, 1 mg
J0178Injection, aflibercept, 1 mg
J0179Injection, brolucizumab-dbll, 1 mg
J0202Injection, alemtuzumab, 1 mg
J0207Injection, amifostine, 500 mg
J0208Injection, sodium thiosulfate (Pedmark), 100 mg
J0218Injection, olipudase alfa-rpcp, 1 mg
J0219Injection, avalglucosidase alfa-ngpt, 4 mg
J0221Injection, alglucosidase alfa, (Lumizyme), 10 mg
J0222Injection, patisiran, 0.1 mg
J0223Injection, givosiran, 0.5 mg
J0224Injection, lumasiran, 0.5 mg
J0257Injection, alpha 1 proteinase inhibitor (human), (GLASSIA), 10 mg
J0280Injection, aminophylline, up to 250 mg
J0283Injection, amiodarone HCl (Nexterone), 30 mg
J0289Injection, amphotericin B liposome, 10 mg
J0291Injection, plazomicin, 5 mg
J0360Injection, hydralazine HCl, up to 20 mg
J0401Injection, aripiprazole, extended release, 1 mg
J0456Injection, azithromycin, 500 mg
J0457Injection, aztreonam, 100 mg
J0475Injection, baclofen, 10 mg
J0476Injection, baclofen, 50 mcg for intrathecal trial
J0480Injection, basiliximab, 20 mg
J0485Injection, belatacept, 1mg
J0490Injection, belimumab, 10 mg
J0491Injection, anifrolumab-fnia, 1 mg
J0500Injection, dicyclomine HCl, up to 20 mg
J0515Injection, benztropine mesylate, per 1 mg
J0517Injection, benralizumab, 1 mg
J0561Injection, penicillin G benzathine, 100,000 units
J0565Injection, bezlotoxumab, 10 mg
J0583Injection, bivalirudin, 1 mg
J0584Injection, burosumab-twza, 1 mg
J0585Injection, onabotulinumtoxinA, 1 unit
J0586Injection, abobotulinumtoxinA, 5 units
J0587Injection, rimabotulinumtoxinB, 100 units
J0588Injection, incobotulinumtoxinA, 1 unit
J0592Injection, buprenorphine HCl, 0.1 mg
J0594Injection, busulfan, 1 mg
J0595Injection, butorphanol tartrate, 1 mg
J0596Injection, C1 esterase inhibitor (recombinant), Ruconest, 10 units
J0597Injection, C1 esterase inhibitor (human), Berinert, 10 units
J0598Injection, C1 esterase inhibitor (human), Cinryze, 10 units
J0599Injection, C1 esterase inhibitor (human), (Haegarda), 10 units
J0600Injection, edetate calcium disodium, up to 1,000 mg
J0612Injection, calcium gluconate, not otherwise specified, 10 mg
J0613Injection, calcium gluconate (WG Critical Care), not therapeutically equivalent to J0612, 10 mg
J0638Injection, canakinumab, 1 mg
J0641Injection, levoleucovorin, not otherwise specified, 0.5 mg
J0642Injection, levoleucovorin (Khapzory), 0.5 mg
J0689Injection, cefazolin sodium (Baxter), not therapeutically equivalent to J0690, 500 mg
J0692Injection, cefepime HCl, 500 mg
J0695Injection, ceftolozane 50 mg and tazobactam 25 mg
J0699Injection, cefiderocol, 10 mg
J0712Injection, ceftaroline fosamil, 10 mg
J0714Injection, ceftazidime and avibactam, 0.5 g/0.125 g
J0717Injection, certolizumab pegol, 1 mg (code may be used for Medicare when drug administered under the direct supervision of a physician, not for use when drug is self-administered)
J0735Injection, clonidine HCl, 1 mg
J0737Injection, clindamycin phosphate (Baxter), not therapeutically equivalent to J0736, 300 mg
J0740Injection, cidofovir, 375 mg
J0741Injection, cabotegravir and rilpivirine, 2 mg/3 mg
J0744Injection, ciprofloxacin for intravenous infusion, 200 mg
J0775Injection, collagenase, clostridium histolyticum, 0.01 mg
J0791Injection, crizanlizumab-tmca, 5 mg
J0834Injection, cosyntropin, 0.25 mg
J0840Injection, crotalidae polyvalent immune fab (ovine), up to 1 g
J0875Injection, dalbavancin, 5 mg
J0877Injection, daptomycin (Hospira), not therapeutically equivalent to J0878, 1 mg
J0878Injection, daptomycin, 1 mg
J0881Injection, darbepoetin alfa, 1 mcg (non-ESRD use)
J0883Injection, argatroban, 1 mg (for non-ESRD use)
J0893Injection, decitabine (Sun Pharma) not therapeutically equivalent to J0894, 1 mg
J0894Injection, decitabine, 1 mg
J0895Injection, deferoxamine mesylate, 500 mg
J0896Injection, luspatercept-aamt, 0.25 mg
J0897Injection, denosumab, 1 mg
J1095Injection, dexamethasone 9%, intraocular, 1 mcg
J1096Dexamethasone, lacrimal ophthalmic insert, 0.1 mg
J1097Phenylephrine 10.16 mg/ml and ketorolac 2.88 mg/ml ophthalmic irrigation solution, 1 ml
J1110Injection, dihydroergotamine mesylate, per 1 mg
J1120Injection, acetazolamide sodium, up to 500 mg
J1165Injection, phenytoin sodium, per 50 mg
J1190Injection, dexrazoxane HCl, per 250 mg
J1201Injection, cetirizine HCl, 0.5 mg
J1205Injection, chlorothiazide sodium, per 500 mg
J1245Injection, dipyridamole, per 10 mg
J1250Injection, dobutamine HCl, per 250 mg
J1265Injection, dopamine HCl, 40 mg
J1300Injection, eculizumab, 10 mg
J1302Injection, sutimlimab-jome, 10 mg
J1303Injection, ravulizumab-cwvz, 10 mg
J1305Injection, evinacumab-dgnb, 5 mg
J1322Injection, elosulfase alfa, 1 mg
J1327Injection, eptifibatide, 5 mg
J1335Injection, ertapenem sodium, 500 mg
J1437Injection, ferric derisomaltose, 10 mg
J1439Injection, ferric carboxymaltose, 1 mg
J1442Injection, filgrastim (G-CSF), excludes biosimilars, 1 mcg
J1447Injection, tbo-filgrastim, 1 mcg
J1448Injection, trilaciclib, 1 mg
J1449Injection, eflapegrastim-xnst, 0.1 mg
J1450Injection, fluconazole, 200 mg
J1451Injection, fomepizole, 15 mg
J1455Injection, foscarnet sodium, per 1,000 mg
J1459Injection, immune globulin (Privigen), intravenous, nonlyophilized (e.g., liquid), 500 mg
J1460Injection, gamma globulin, intramuscular, 1 cc
J1551Injection, immune globulin (Cutaquig), 100 mg
J1554Injection, immune globulin (Asceniv), 500 mg
J1555Injection, immune globulin (Cuvitru), 100 mg
J1556Injection, immune globulin (Bivigam), 500 mg
J1558Injection, immune globulin (xembify), 100 mg
J1559Injection, immune globulin (Hizentra), 100 mg
J1561Injection, immune globulin, (Gamunex/Gamunex-C/Gammaked), nonlyophilized (e.g., liquid), 500 mg
J1568Injection, immune globulin, (Octagam), intravenous, nonlyophilized (e.g., liquid), 500 mg
J1569Injection, immune globulin, (Gammagard liquid), nonlyophilized, (e.g., liquid), 500 mg
J1570Injection, ganciclovir sodium, 500 mg
J1571Injection, hepatitis B immune globulin (Hepagam B), intramuscular, 0.5 ml
J1573Injection, hepatitis B immune globulin (Hepagam B), intravenous, 0.5 ml
J1575Injection, immune globulin/hyaluronidase, 100 mg immuneglobulin
J1576Injection, immune globulin (Panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mg
J1602Injection, golimumab, 1 mg, for intravenous use
J1610Injection, glucagon HCl, per 1 mg
J1611Injection, glucagon HCl (Fresenius Kabi), not therapeutically equivalent to J1610, per 1 mg
J1640Injection, hemin, 1 mg
J1652Injection, fondaparinux sodium, 0.5 mg
J1670Injection, tetanus immune globulin, human, up to 250 units
J1743Injection, idursulfase, 1 mg
J1745Injection, infliximab, excludes biosimilar, 10 mg
J1746Injection, ibalizumab-uiyk, 10 mg
J1747Injection, spesolimab-sbzo, 1 mg
J1750Injection, iron dextran, 50 mg
J1756Injection, iron sucrose, 1 mg
J1786Injection, imiglucerase, 10 units
J1805Injection, esmolol HCl, 10 mg
J1823Injection, inebilizumab-cdon, 1 mg
J1826Injection, interferon beta-1a, 30 mcg
J1885Injection, ketorolac tromethamine, per 15 mg
J1921Injection, labetalol HCl (Hikma) not therapeutically equivalent to J1920, 5 mg
J1930Injection, lanreotide, 1 mg
J1931Injection, laronidase, 0.1 mg
J1932Injection, lanreotide, (Cipla), 1 mg
J1940Injection, furosemide, up to 20 mg
J1943Injection, aripiprazole lauroxil, (Aristada Initio), 1 mg
J1953Injection, levetiracetam, 10 mg
J1954Injection, leuprolide acetate for depot suspension (Cipla), 7.5 mg
J1956Injection, levofloxacin, 250 mg
J2001Injection, lidocaine HCl for intravenous infusion, 10 mg
J2175Injection, meperidine HCl, per 100 mg
J2182Injection, mepolizumab, 1 mg
J2185Injection, meropenem, 100 mg
J2186Injection, meropenem, vaborbactam, 10 mg/10 mg, (20 mg)
J2212Injection, methylnaltrexone, 0.1 mg
J2248Injection, micafungin sodium, 1 mg
J2270Injection, morphine sulfate, up to 10 mg
J2272Injection, morphine sulfate (Fresenius Kabi) not therapeutically equivalent to J2270, up to 10 mg
J2274Injection, morphine sulfate, preservative free for epidural or intrathecal use, 10 mg
J2278Injection, ziconotide, 1 mcg
J2305Injection, nitroglycerin, 5 mg
J2323Injection, natalizumab, 1 mg
J2327Injection, risankizumab-rzaa, intravenous, 1 mg
J2329Injection, ublituximab-xiiy, 1mg
J2353Injection, octreotide, depot form for intramuscular injection, 1 mg
J2356Injection, tezepelumab-ekko, 1 mg
J2357Injection, omalizumab, 5 mg
J2358Injection, olanzapine, long-acting, 1 mg
J2359Injection, olanzapine, 0.5 mg
J2360Injection, orphenadrine citrate, up to 60 mg
J2371Injection, phenylephrine HCl, 20 mcg
J2372Injection, phenylephrine HCl (Biorphen), 20 mcg
J2403Chloroprocaine HCl ophthalmic, 3% gel, 1 mg
J2406Injection, oritavancin (Kimyrsa), 10 mg
J2425Injection, palifermin, 50 mcg
J2426Injection, paliperidone palmitate extended release (Invega Sustenna), 1 mg
J2430Injection, pamidronate disodium, per 30 mg
J2506Injection, pegfilgrastim, excludes biosimilar, 0.5 mg
J2507Injection, pegloticase, 1 mg
J2560Injection, phenobarbital sodium, up to 120 mg
J2562Injection, plerixafor, 1 mg
J2704Injection, propofol, 10 mg
J2720Injection, protamine sulfate, per 10 mg
J2765Injection, metoclopramide HCl, up to 10 mg
J2777Injection, faricimab-svoa, 0.1 mg
J2778Injection, ranibizumab, 0.1 mg
J2779Injection, ranibizumab, via intravitreal implant (Susvimo), 0.1 mg
J2781Injection, pegcetacoplan, intravitreal, 1 mg
J2783Injection, rasburicase, 0.5 mg
J2785Injection, regadenoson, 0.1 mg
J2786Injection, reslizumab, 1 mg
J2792Injection, Rho D immune globulin, intravenous, human, solvent detergent, 100 IU
J2794Injection, risperidone (RISPERDAL CONSTA), 0.5 mg
J2795Injection, ropivacaine HCl, 1 mg
J2796Injection, romiplostim, 10 mcg
J2800Injection, methocarbamol, up to 10 ml
J2805Injection, sincalide, 5 mcg
J2820Injection, sargramostim (GM-CSF), 50 mcg
J2850Injection, secretin, synthetic, human, 1 mcg
J2860Injection, siltuximab, 10 mg
J2916Injection, sodium ferric gluconate complex in sucrose injection, 12.5 mg
J2993Injection, reteplase, 18.1 mg
J3010Injection, fentanyl citrate, 0.1 mg
J3032Injection, eptinezumab-jjmr, 1 mg
J3095Injection, telavancin, 10 mg
J3101Injection, tenecteplase, 1 mg
J3111Injection, romosozumab-aqqg, 1 mg
J3145Injection, testosterone undecanoate, 1 mg
J3241Injection, teprotumumab-trbw, 10 mg
J3243Injection, tigecycline, 1 mg
J3245Injection, tildrakizumab, 1 mg
J3262Injection, tocilizumab, 1 mg
J3299Injection, triamcinolone acetonide (Xipere), 1 mg
J3300Injection, triamcinolone acetonide, preservative free, 1 mg
J3304Injection, triamcinolone acetonide, preservative-free, extended-release, microsphere formulation, 1 mg
J3357Ustekinumab, for subcutaneous injection, 1 mg
J3358Ustekinumab, for intravenous injection, 1 mg
J3380Injection, vedolizumab, IV, 1 mg
J3385Injection, velaglucerase alfa, 100 units
J3396Injection, verteporfin, 0.1 mg
J3410Injection, hydroxyzine HCl, up to 25 mg
J3430Injection, phytonadione (vitamin K), per 1 mg
J3465Injection, voriconazole, 10 mg
J3471Injection, hyaluronidase, ovine, preservative free, per 1 USP unit (up to 999 USP units)
J3473Injection, hyaluronidase, recombinant, 1 USP unit
J3486Injection, ziprasidone mesylate, 10 mg
J3489Injection, zoledronic acid, 1 mg
J7168Prothrombin complex concentrate (human), Kcentra, per IU of Factor IX activity
J7169Injection, coagulation Factor Xa (recombinant), inactivated-zhzo (Andexxa), 10 mg
J7170Injection, emicizumab-kxwh, 0.5 mg
J7175Injection, Factor X, (human), 1 IU
J7177Injection, human fibrinogen concentrate (Fibryga), 1 mg
J7179Injection, von Willebrand factor (recombinant), (Vonvendi), 1 IU VWF:RCo
J7180Injection, Factor XIII (antihemophilic factor, human), 1 IU
J7181Injection, Factor XIII A-subunit, (recombinant), per IU
J7182Injection, Factor VIII, (antihemophilic factor, recombinant), (NovoEight), per IU
J7183Injection, von Willebrand factor complex (human), Wilate, 1 IU VWF:RCO
J7185Injection, Factor VIII (antihemophilic factor, recombinant) (Xyntha), per IU
J7186Injection, antihemophilic Factor VIII/von Willebrand factor complex (human), per Factor VIII IU
J7187Injection, von Willebrand factor complex (Humate-P), per IU VWF:RCO
J7188Injection, Factor VIII (antihemophilic factor, recombinant) (Obizur), per IU
J7189Factor VIIa (antihemophilic factor, recombinant), (NovoSeven RT), 1 mcg
J7190Factor VIII (antihemophilic factor, human) per IU
J7193Factor IX (antihemophilic factor, purified, nonrecombinant) per IU
J7194Factor IX complex, per IU
J7197Antithrombin III (human), per IU
J7198Antiinhibitor, per IU
J7200Injection, Factor IX, (antihemophilic factor, recombinant), Rixubis, per IU
J7201Injection, Factor IX, Fc fusion protein, (recombinant), Alprolix, 1 IU
J7202Injection, Factor IX, albumin fusion protein, (recombinant), Idelvion, 1 IU
J7203Injection Factor IX, (antihemophilic factor, recombinant), glycoPEGylated, (Rebinyn), 1 IU
J7204Injection, Factor VIII, antihemophilic factor (recombinant), (Esperoct), glycopegylated-exei, per IU
J7205Injection, Factor VIII Fc fusion protein (recombinant), per IU
J7207Injection, Factor VIII, (antihemophilic factor, recombinant), PEGylated, 1 IU
J7208Injection, Factor VIII, (antihemophilic factor, recombinant), PEGylated-aucl, (Jivi), 1 IU
J7209Injection, Factor VIII, (antihemophilic factor, recombinant), (Nuwiq), 1 IU
J7210Injection, Factor VIII, (antihemophilic factor, recombinant), (Afstyla), 1 IU
J7211Injection, Factor VIII, (antihemophilic factor, recombinant), (Kovaltry), 1 IU
J7212Factor VIIa (antihemophilic factor, recombinant)-jncw (Sevenfact), 1 mcg
J7213Injection, coagulation factor IX (recombinant), Ixinity, 1 IU
J7214Injection, Factor VIII/von Willebrand factor complex, recombinant (Altuviiio), per Factor VIII IU
J7312Injection, dexamethasone, intravitreal implant, 0.1 mg
J7313Injection, fluocinolone acetonide, intravitreal implant (Iluvien), 0.01 mg
J7314Injection, fluocinolone acetonide, intravitreal implant (Yutiq), 0.01 mg
J7315Mitomycin, opthalmic, 0.2 mg
J7336Capsaicin 8% patch, per sq cm
J7342Instillation, ciprofloxacin otic suspension, 6 mg
J7351Injection, bimatoprost, intracameral implant, 1 mcg
J7352Afamelanotide implant, 1 mg
J7402Mometasone furoate sinus implant, (Sinuva), 10 mcg
J7504Lymphocyte immune globulin, antithymocyte globulin, equine, parenteral, 250 mg
J7511Lymphocyte immune globulin, antithymocyte globulin, rabbit, parenteral, 25 mg
J7516Injection, cyclosporine, 250 mg
J7519Injection, mycophenolate mofetil, 10 mg
J7525Tacrolimus, parenteral, 5 mg
J9015Injection, aldesleukin, per single use vial
J9017Injection, arsenic trioxide, 1 mg
J9021Injection, asparaginase, recombinant, (Rylaze), 0.1 mg
J9022Injection, atezolizumab, 10 mg
J9023Injection, avelumab, 10 mg
J9025Injection, azacitidine, 1 mg
J9027Injection, clofarabine, 1 mg
J9029Intravesical instillation, nadofaragene firadenovec-vncg, per therapeutic dose
J9030BCG live intravesical instillation, 1 mg
J9032Injection, belinostat, 10 mg
J9033Injection, bendamustine HCl (Treanda), 1 mg
J9035Injection, bevacizumab, 10 mg
J9037Injection, belantamab mafodontin-blmf, 0.5 mg
J9039Injection, blinatumomab, 1 mcg
J9040Injection, bleomycin sulfate, 15 units
J9041Injection, bortezomib (Velcade), 0.1 mg
J9042Injection, brentuximab vedotin, 1 mg
J9043Injection, cabazitaxel, 1 mg
J9046Injection, bortezomib (Dr. Reddy's), not therapeutically equivalent to J9041, 0.1 mg
J9047Injection, carfilzomib, 1 mg
J9048Injection, bortezomib (Fresenius Kabi), not therapeutically equivalent to J9041, 0.1 mg
J9049Injection, bortezomib (Hospira), not therapeutically equivalent to J9041, 0.1 mg
J9050Injection, carmustine, 100 mg
J9051Injection, bortezomib (MAIA), not therapeutically equivalent to J9041, 0.1 mg
J9055Injection, cetuximab, 10 mg
J9057Injection, copanlisib, 1 mg
J9061Injection, amivantamab-vmjw, 2 mg
J9063Injection, mirvetuximab soravtansine-gynx, 1 mg
J9065Injection, cladribine, per 1 mg
J9072Injection, cyclophosphamide (Dr. Reddy's), 5 mg
J9118Injection, calaspargase pegol-mknl, 10 units
J9119Injection, cemiplimab-rwlc, 1 mg
J9120Injection, dactinomycin, 0.5 mg
J9130Dacarbazine, 100 mg
J9144Injection, daratumumab, 10 mg and hyaluronidase-fihj
J9145Injection, daratumumab, 10 mg
J9150Injection, daunorubicin, 10 mg
J9153Injection, liposomal, 1 mg daunorubicin and 2.27 mg cytarabine
J9155Injection, degarelix, 1 mg
J9173Injection, durvalumab, 10 mg
J9176Injection, elotuzumab, 1 mg
J9177Injection, enfortumab vedotin-ejfv, 0.25 mg
J9178Injection, epirubicin HCl, 2 mg
J9179Injection, eribulin mesylate, 0.1 mg
J9185Injection, fludarabine phosphate, 50 mg
J9201Injection, gemcitabine HCl, not otherwise specified, 200 mg
J9202Goserelin acetate implant, per 3.6 mg
J9203Injection, gemtuzumab ozogamicin, 0.1 mg
J9204Injection, mogamulizumab-kpkc, 1 mg
J9205Injection, irinotecan liposome, 1 mg
J9206Injection, irinotecan, 20 mg
J9207Injection, ixabepilone, 1 mg
J9208Injection, ifosfamide, 1 g
J9210Injection, emapalumab-lzsg, 1 mg
J9217Leuprolide acetate (for depot suspension), 7.5 mg
J9223Injection, lurbinectedin, 0.1 mg
J9226Histrelin implant (Supprelin LA), 50 mg
J9227Injection, isatuximab-irfc, 10 mg
J9228Injection, ipilimumab, 1 mg
J9229Injection, inotuzumab ozogamicin, 0.1 mg
J9246Injection, melphalan (Evomela), 1 mg
J9248Injection, melphalan (Hepzato), 1 mg
J9259Injection, paclitaxel protein-bound particles (American Regent) not therapeutically equivalent to J9264, 1 mg
J9261Injection, nelarabine, 50 mg
J9262Injection, omacetaxine mepesuccinate, 0.01 mg
J9263Injection, oxaliplatin, 0.5 mg
J9264Injection, paclitaxel protein-bound particles, 1 mg
J9266Injection, pegaspargase, per single dose vial
J9268Injection, pentostatin, 10 mg
J9269Injection, tagraxofusp-erzs, 10 mcg
J9271Injection, pembrolizumab, 1 mg
J9272Injection, dostarlimab-gxly, 10 mg
J9273Injection, tisotumab vedotin-tftv, 1 mg
J9274Injection, tebentafusp-tebn, 1 mcg
J9281Mitomycin pyelocalyceal instillation, 1 mg
J9286Injection, glofitamab-gxbm, 2.5 mg
J9294Injection, pemetrexed (Hospira), not therapeutically equivalent to J9305, 10 mg
J9295Injection, necitumumab, 1 mg
J9296Injection, pemetrexed (Accord), not therapeutically equivalent to J9305, 10 mg
J9297Injection, pemetrexed (Sandoz), not therapeutically equivalent to J9305, 10 mg
J9298Injection, nivolumab and relatlimab-rmbw, 3 mg/1 mg
J9299Injection, nivolumab, 1 mg
J9301Injection, obinutuzumab, 10 mg
J9302Injection, ofatumumab, 10 mg
J9303Injection, panitumumab, 10 mg
J9305Injection, pemetrexed, NOS, 10 mg
J9306Injection, pertuzumab, 1 mg
J9307Injection, pralatrexate, 1 mg
J9308Injection, ramucirumab, 5 mg
J9309Injection, polatuzumab vedotin-piiq, 1 mg
J9311Injection, rituximab 10 mg and hyaluronidase
J9312Injection, rituximab, 10 mg
J9313Injection, moxetumomab pasudotox-tdfk, 0.01 mg
J9314Injection, pemetrexed (Teva) not therapeutically equivalent to J9305, 10 mg
J9316Injection, pertuzumab, trastuzumab, and hyaluronidase-zzxf, per 10 mg
J9317Injection, sacituzumab govitecan-hziy, 2.5 mg
J9318Injection, romidepsin, nonlyophilized, 0.1 mg
J9319Injection, romidepsin, lyophilized, 0.1 mg
J9320Injection, streptozocin, 1 g
J9321Injection, epcoritamab-bysp, 0.16 mg
J9322Injection, pemetrexed (BluePoint) not therapeutically equivalent to J9305, 10 mg
J9323Injection, pemetrexed ditromethamine, 10 mg
J9325Injection, talimogene laherparepvec, per 1 million plaque forming units
J9328Injection, temozolomide, 1 mg
J9330Injection, temsirolimus, 1 mg
J9331Injection, sirolimus protein-bound particles, 1 mg
J9332Injection, efgartigimod alfa-fcab, 2 mg
J9333Injection, rozanolixizumab-noli, 1 mg
J9334Injection, efgartigimod alfa, 2 mg and hyaluronidase-qvfc
J9340Injection, thiotepa, 15 mg
J9345Injection, retifanlimab-dlwr, 1 mg
J9347Injection, tremelimumab-actl, 1 mg
J9348Injection, naxitamab-gqgk, 1 mg
J9349Injection, tafasitamab-cxix, 2 mg
J9350Injection, mosunetuzumab-axgb, 1 mg
J9352Injection, trabectedin, 0.1 mg
J9353Injection, margetuximab-cmkb, 5 mg
J9354Injection, ado-trastuzumab emtansine, 1 mg
J9355Injection, trastuzumab, excludes biosimilar, 10 mg
J9356Injection, trastuzumab, 10 mg and hyaluronidase-oysk
J9357Injection, valrubicin, intravesical, 200 mg
J9358Injection, fam-trastuzumab deruxtecan-nxki, 1 mg
J9359Injection, loncastuximab tesirine-lpyl, 0.075 mg
J9370Vincristine sulfate, 1 mg
J9380Injection, teclistamab-cqyv, 0.5 mg
J9381Injection, teplizumab-mzwv, 5 mcg
J9390Injection, vinorelbine tartrate, 10 mg
J9393Injection, fulvestrant (Teva) not therapeutically equivalent to J9395, 25 mg
J9394Injection, fulvestrant (Fresenius Kabi) not therapeutically equivalent to J9395, 25 mg
J9395Injection, fulvestrant, 25 mg
J9400Injection, ziv-aflibercept, 1 mg
J9600Injection, porfimer sodium, 75 mg
Q0138Injection, ferumoxytol, for treatment of iron deficiency anemia, 1 mg (non-ESRD use)
Q2009Injection, fosphenytoin, 50 mg phenytoin equivalent
Q2049Injection, doxorubicin HCl, liposomal, imported Lipodox, 10 mg
Q3027Injection, interferon beta-1a, 1 mcg for intramuscular use
Q5101Injection, filgrastim-sndz, biosimilar, (Zarxio), 1 mcg
Q5103Injection, infliximab-dyyb, biosimilar, (Inflectra), 10 mg
Q5104Injection, infliximab-abda, biosimilar, (Renflexis), 10 mg
Q5107Injection, bevacizumab-awwb, biosimilar, (Mvasi), 10 mg
Q5108Injection, pegfilgrastim-jmdb (Fulphila), biosimilar, 0.5 mg
Q5110Injection, filgrastim-aafi, biosimilar, (Nivestym), 1 mcg
Q5111Injection, pegfilgrastim-cbqv (Udenyca), biosimilar, 0.5 mg
Q5115Injection, rituximab-abbs, biosimilar, (Truxima), 10 mg
Q5118Injection, bevacizumab-bvzr, biosimilar, (Zirabev), 10 mg
Q5119Injection, rituximab-pvvr, biosimilar, (RUXIENCE), 10 mg
Q5120Injection, pegfilgrastim-bmez (ZIEXTENZO), biosimilar, 0.5 mg
Q5121Injection, infliximab-axxq, biosimilar, (AVSOLA), 10 mg
Q5122Injection, pegfilgrastim-apgf (Nyvepria), biosimilar, 0.5 mg
Q5123Injection, rituximab-arrx, biosimilar, (Riabni), 10 mg
Q5124Injection, ranibizumab-nuna, biosimilar, (Byooviz), 0.1 mg
Q5125Injection, filgrastim-ayow, biosimilar, (Releuko), 1 mcg
Q5126Injection, bevacizumab-maly, biosimilar, (Alymsys), 10 mg
Q5127Injection, pegfilgrastim-fpgk (Stimufend), biosimilar, 0.5 mg
Q5128Injection, ranibizumab-eqrn (Cimerli), biosimilar, 0.1 mg
Q5129Injection, bevacizumab-adcd (Vegzelma), biosimilar, 10 mg
Q5130Injection, pegfilgrastim-pbbk (Fylnetra), biosimilar, 0.5 mg

FAQ

Frequently asked questions

What is the JW modifier?

The JW modifier reports the amount of a drug or biological discarded from a single-dose container or single-use package. The discarded units are billed on a separate claim line so Medicare can pay for the wasted amount.

What is the JZ modifier?

The JZ modifier attests that no amount of the drug was discarded from a single-dose container. CMS requires it on these claims whenever there is no wastage to report.

When is the JZ modifier mandatory?

Since July 1, 2023, CMS requires the JZ modifier on all claims for separately payable drugs from single-dose containers when there is no discarded amount. Claims missing the modifier may be subject to edits or audits.

Where do the JW and JZ modifiers go on a claim?

On the CMS-1500 form, JW and JZ are entered in box 24(D) next to the corresponding HCPCS code. The discarded amount (JW) is reported on its own line with the wasted units.

Why does drug wastage need to be billed?

Medicare Part B pays for both the administered and the discarded amounts of a drug from a single-dose container, so providers report the wasted units with the JW modifier to be reimbursed for them. Accurate reporting also feeds the Infrastructure Investment and Jobs Act (IIJA) refund program, under which manufacturers must refund Medicare for discarded amounts of certain single-dose drugs that exceed an applicable percentage (generally 10%) of total allowed charges each quarter.

Look up what Part B pays per billing unit →