Linezolid J Code: J2020
Injection, linezolid, 200 mg
Q4 2026 Medicare Payment Limit for J2020, effective October 1, 2026: $2.431 per HCPCS billing unit, up 7.2% from $2.268. From CMS's final file.
Drug & Product Overview
About Linezolid
Linezolid is a medication aligned to the HCPCS J Code: J2020 for billing, pricing, and reimbursement purposes in the United States. It is an Antibiotic drug administered via the intravenous route and manufactured by multiple companies.
According to CMS Drug Use Information: Linezolid is an antibiotic used to treat certain serious bacterial infections. It works by stopping the growth of bacteria. Linezolid also belongs to a class of drugs known as MAO inhibitors. It can increase the levels of certain natural substances in the body (such as dopamine, norepinephrine, serotonin) which can increase the chance of certain side effects and food and drug interactions. See How to Use, Side Effects, and Drug Interactions sections for more details.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 5 of 15 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 00009-4992-02 | Zyvox | Pfizer Inc | 30 | 600 MG / 300 ML |
| 00009-5140-04 | Zyvox | Pharmacia & Upjohn Company LLC | 30 | 600 MG / 300 ML |
| 00143-9534-10 | Linezolid | Hikma Pharmaceuticals USA Inc. | 30 | 600 MG / 300 ML |
| 00781-3433-95 | Linezolid | Sandoz Inc | 30 | 600 MG / 300 ML |
| 25021-0169-87 | Linezolid | Sagent Pharmaceuticals | 30 | 600 MG / 300 ML |
| •••••-••••-•• Log in to view | Linezolid | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | Linezolid | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | Linezolid | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
Linezolid Pricing & Reimbursement
National median reimbursement across major commercial payers.
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Login to use the calculator →Linezolid 505(b)(2) Information:
| HCPCS Code | Manufacturer | Active Ingredient | HCPCS Description |
|---|---|---|---|
| J2020 | Generic Code (Multiple Manufacturers) | Linezolid | Injection, linezolid, 200 mg |
| J2021 | Generic Code (Multiple Manufacturers) | Linezolid | Injection, linezolid (hospira), not therapeutically equivalent to j2020, 200 mg |
Linezolid CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96365 | Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour |
| 96366 | Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure) |
CMS does not include Linezolid (J2020) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2020. Wastage billing guide →
Linezolid Medically Unlikely Edits (MUE)
The most billing units of J2020 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 200 mg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
Linezolid Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
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Does billing Linezolid require JZ/JW wastage modifiers?
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