Morphine Sulfate J Code: J2270
Injection, morphine sulfate, up to 10 mg
Q4 2026 Medicare Payment Limit for J2270, effective October 1, 2026: $7.259 per HCPCS billing unit, down 10.2% from $8.087. From CMS's final file.
Drug & Product Overview
About Morphine Sulfate
Morphine Sulfate is a medication aligned to the HCPCS J Code: J2270 for billing, pricing, and reimbursement purposes in the United States. Classified under Opioid Analgesic, it is administered via the epidural, intramuscular, intrathecal, or intravenous routes and manufactured by multiple companies.
According to CMS Drug Use Information: This medication is used to treat severe pain. Morphine belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 5 of 23 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 00409-1134-03 | Morphine Sulfate | Pfizer Inc | 100 | 50 MG |
| 00409-1890-01 | Morphine Sulfate | Hospira, Inc. | 2 | 2 MG / 1 ML |
| 00409-1892-01 | Morphine Sulfate | Pfizer Inc | 8 | 8 MG |
| 00641-6125-25 | Morphine Sulfate | Hikma Pharmaceuticals USA Inc. | 10 | 4 MG / 1 ML |
| 72572-0440-25 | Morphine Sulfate | Civica, Inc. | 10 | 4 MG / 1 ML |
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Morphine Sulfate Pricing & Reimbursement
National median reimbursement across major commercial payers.
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Login to use the calculator →Morphine Sulfate 505(b)(2) Information:
| HCPCS Code | Manufacturer | Active Ingredient | HCPCS Description |
|---|---|---|---|
| J2270 | Generic Code (Multiple Manufacturers) | Morphine Sulfate | Injection, morphine sulfate, up to 10 mg |
| J2272 | Fresenius Kabi | Morphine Sulfate | Injection, morphine sulfate (fresenius kabi), not therapeutically equivalent to j2270, up to 10 mg |
| J2274 | Generic Code (Multiple Manufacturers) | Morphine Sulfate | Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg |
Morphine Sulfate CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular |
| 96374 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug |
CMS has identified Morphine Sulfate (J2270) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →
Morphine Sulfate Medically Unlikely Edits (MUE)
The most billing units of J2270 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg. The limit is different in the office and the hospital. Use the one for your setting.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
Morphine Sulfate Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
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Does billing Morphine Sulfate require JZ/JW wastage modifiers?
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