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Updated July 1st, 2026

DURAMORPH J Code: J2274

Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg

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Q4 2026 Medicare Payment Limit for J2274, effective October 1, 2026: $16.044 per HCPCS billing unit, down 15.2% from $18.914. From CMS's final file.

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Medicare Payment Limit ?
$18.914
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
11
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Drug & Product Overview

HCPCS Descriptor Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg
HCPCS Added Date January 1, 2015
Manufacturer Multiple Manufacturers
Route of Administration Epidural, Intramuscular, Intrathecal, Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection | Injection, Solution

About DURAMORPH

Duramorph is a medication aligned to the HCPCS J Code: J2274 for billing, pricing, and reimbursement purposes in the United States. This Opioid Analgesic medication is administered via the epidural, intramuscular, intrathecal, or intravenous routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to treat severe pain. Morphine belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 11 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00409-3814-12 Morphine Sulfate Hospira, Inc. 3 5 MG / 10 ML
00409-3815-12 Morphine Sulfate Hospira, Inc. 5 10 MG / 10 ML
00641-6019-10 Duramorph Hikma Pharmaceuticals USA Inc. 10 10 MG / 10 ML
00641-6040-01 Infumorph 500 Hikma Pharmaceuticals USA Inc. 50 500 MG / 20 ML
66794-0160-02 Mitigo Piramal Critical Care, Inc. 20 200 MG / 20 ML
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DURAMORPH Pricing & Reimbursement

J2274 Private Payer Reimbursement
$13.37 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Morphine Sulfate 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J2270 Generic Code (Multiple Manufacturers) Morphine Sulfate Injection, morphine sulfate, up to 10 mg
J2272 Fresenius Kabi Morphine Sulfate Injection, morphine sulfate (fresenius kabi), not therapeutically equivalent to j2270, up to 10 mg
J2274 Generic Code (Multiple Manufacturers) Morphine Sulfate Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg

DURAMORPH CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96450 Chemotherapy administration, into CNS (eg, intrathecal), requiring and including spinal puncture
JW / JZ modifiers apply

CMS has identified Duramorph (J2274) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

DURAMORPH Medically Unlikely Edits (MUE)

The most billing units of J2274 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
250 units / day
= 2,500 mg per day
Hospital Outpatient
100 units / day
= 1,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

DURAMORPH Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

epidural or intrathecal pain management intractable chronic pain pain management without loss of motor, sensory, or sympathetic function pain severe enough to require an opioid analgesic
Drug Class
Full Opioid Agonists [MoA]Opioid Agonist [EPC]

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Frequently Asked Questions

Is there an available Duramorph billing and coding guide?
Billing and coding information for DURAMORPH can be found through Multiple Manufacturers. Visit Here →
Are there any available Duramorph patient assistance programs?
Our team did not identify a source for Duramorph patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Duramorph prescribing information?
DURAMORPH prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Duramorph side effect information?
Our team has not yet identified a source of side effects information for DURAMORPH. Please check back in a few weeks.
Does billing DURAMORPH require JZ/JW wastage modifiers?
CMS has identified DURAMORPH(J2274) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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