HYDROMORPHONE HCL J Code: J1171

Drug & Product Overview

HCPCS Descriptor Injection, hydromorphone, 0.1 mg

HCPCS Added Date October 1, 2024

Manufacturer Multiple Manufacturers

Route of Administration Intramuscular, Intravenous, Subcutaneous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose, Multi-Dose

Dosage Form Injection | Injection, Solution

About HYDROMORPHONE HCL

Hydromorphone HCL is a medication aligned to the HCPCS J Code: J1171 for billing, pricing, and reimbursement purposes in the United States. It is an Opioid Analgesic drug administered via the intramuscular, intravenous, or subcutaneous routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to relieve moderate to severe pain. Hydromorphone is an opioid pain reliever. It acts on certain centers in the brain to give you pain relief.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 53 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00409-1283-31	Hydromorphone Hydrochloride	Hospira, Inc.	100	1 MG / 1 ML
00409-1304-31	Hydromorphone Hydrochloride	Hospira, Inc.	400	4 MG / 1 ML
00641-2341-41	Hydromorphone Hydrochloride	Hikma Pharmaceuticals USA Inc.	400	40 MG / 20 ML
00703-0018-01	Hydromorphone Hydrochloride	Teva Parenteral Medicines, Inc.	5000	500 MG / 50 ML
63323-0851-10	Hydromorphone Hydrochloride	Fresenius Kabi USA, LLC	1000	10 MG / 1 ML
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HYDROMORPHONE HCL Pricing & Reimbursement

J1171 Private Payer Reimbursement

$0.33 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Hydromorphone Hydrochloride 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J1171	Generic Code (Multiple Manufacturers)	Hydromorphone Hydrochloride	Injection, hydromorphone, 0.1 mg

HYDROMORPHONE HCL CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
96374	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

HYDROMORPHONE HCL Medically Unlikely Edits (MUE)

The most billing units of J1171 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

240 units / day

= 24 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

HYDROMORPHONE HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Pain severe enough to require an opioid analgesic Pain severe enough to require an opioid analgesic and for which alternate treatments are inadequate Pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate Severe pain requiring opioid analgesic moderate to severe pain (surgery, cancer, trauma, biliary colic, myocardial infarction, burns, renal colic) pain severe enough to require an opioid analgesic

Drug Class

Full Opioid Agonists [MoA]Opioid Agonist [EPC]

Frequently Asked Questions

Is there an available HYDROMORPHONE HCL billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for HYDROMORPHONE HCL.

Are there any available HYDROMORPHONE HCL patient assistance programs?

HYDROMORPHONE HCL patient assistance information can be found through Pfizer Inc. Visit Here →

Where can I find HYDROMORPHONE HCL prescribing information?

HYDROMORPHONE HCL prescribing information can be found at the link below. Visit Here →

Where can I find HYDROMORPHONE HCL side effect information?

Information on the side effects of HYDROMORPHONE HCL can be found at the below link.

Does billing HYDROMORPHONE HCL require JZ/JW wastage modifiers?

CMS does not include HYDROMORPHONE HCL (J1171) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1171. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.