CPT Administration Code: 96374 | Drug Injection

Code Overview

CPT® administration code details for 96374.

CPT Code Descriptor Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug

Code Category Drug Injection

Route / Technique Intravenous Push

Code Type Initial / Primary Code

About Drug Injection – 96374

CPT 96374 reports the intravenous push administration of a therapeutic, prophylactic, or diagnostic substance, other than chemotherapy or a biologic requiring chemotherapy-level administration coding. It is designated as an initial service code, used when IV push is the sole or primary method of administration during the encounter. An IV push is defined as an injection in which the physician or qualified staff is continuously present to administer the substance and observe the patient, or an infusion lasting 15 minutes or less.

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96374 RVU Breakdown & Medicare Reimbursement

Based on the CY 2026 CMS Physician Fee Schedule. National payment amounts, before geographic (GPCI) adjustment.

Component	Facility	Non-Facility
Work RVU — physician work	0.18	0.18
Practice Expense RVU — staff, supplies, equipment	0.93	0.93
Malpractice RVU — professional liability	0.02	0.02
Total RVUs	1.13	1.13
Medicare Payment — Total RVUs × $33.4009 CF	$37.74	$37.74

CY 2026 Medicare Conversion Factor: $33.4009. Facility and non-facility practice-expense RVUs are equal for this code.

96374 Locality-Adjusted Rates

Medicare payment varies by locality via GPCI adjustment. Log in to view rates for all 100+ Medicare localities.

Medicare Locality	Facility	Non-Facility
National (unadjusted)	$37.74	$37.74
Los Angeles–Long Beach, CA
Manhattan, NY
Houston, TX
Miami, FL

Related Administration Codes

The therapeutic injection code family. Report one initial code per encounter; add-on codes are listed separately in addition to the primary procedure.

CPT Code	Description	Type
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular	Initial
96374This page	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug	Initial
96377	Application of on-body injector (includes cannula insertion) for timed subcutaneous injection	Initial

Drugs Commonly Billed with 96374

HCPCS-coded drugs frequently administered under this CPT code. The list below is not exhaustive.

HCPCS Code	Drug	HCPCS Descriptor
J2997	ACTIVASE	Injection, alteplase recombinant, 1 mg
J0163	ADRENALIN	Injection, epinephrine in sodium chloride (endo), 0.1 mg
J0216	ALFENTA	Injection, alfentanil hydrochloride, 500 micrograms
J0300	AMYTAL SODIUM	Injection, amobarbital, up to 125 mg
J0184	BARHEMSYS	Injection, amisulpride, 1 mg

Frequently Asked Questions

What are CPT Administration Codes?

CPT administration codes cover the work of giving a drug to a patient, such as an injection or an infusion. The drug itself is billed with its HCPCS J-code, and the administration is billed with a CPT code. Both go on the same claim. Learn More →

What is the Medicare Conversion Factor?

The conversion factor is the dollar amount CMS uses to turn a code's total RVUs into a Medicare payment. This page uses the CY 2026 conversion factor of $33.4009. CMS updates it every year in the Physician Fee Schedule final rule.

Facility vs. Non-Facility?

The non-facility rate applies in a physician office, where the practice pays for its own staff, supplies, and equipment, so the rate is usually higher. The facility rate applies in hospital outpatient departments and ASCs, where the facility bills for those costs separately.

How do I decide which administration code to use?

Pick the code that matches the type of drug, the route, and how long the administration takes. Start from the highest-ranking service you performed, then add the appropriate add-on codes for extra time or extra drugs. Manufacturer billing and coding guides often list suggested administration codes.

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CPT Administration Code: 96374 – Drug Injection