Home › Drug Codes › J Codes › J1626 · GRANISETRON HCL
Updated July 1st, 2026

GRANISETRON HCL J Code: J1626

Injection, granisetron hydrochloride, 100 mcg

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Q4 2026 Medicare Payment Limit for J1626, effective October 1, 2026: $0.16 per HCPCS billing unit, down 19.6% from $0.199. From CMS's final file.

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Medicare Payment Limit ?
$0.199
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
6
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Drug & Product Overview

HCPCS Descriptor Injection, granisetron hydrochloride, 100 mcg
HCPCS Added Date January 1, 1998
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose, Multi-Dose
Dosage Form Injection | Injection, Solution | Not Available

About GRANISETRON HCL

Granisetron HCL is a medication aligned to the HCPCS J Code: J1626 for billing, pricing, and reimbursement purposes in the United States. This Anti-Emetic medication is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). It is also used to prevent and treat nausea and vomiting after surgery in adults. Granisetron works by blocking one of the body's natural substances (serotonin) that can cause vomiting.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 6 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00143-9744-10 Granisetron Hydrochloride Hikma Pharmaceuticals USA Inc. 100 1000 MCG / 1 ML
00143-9745-05 Granisetron Hydrochloride Hikma Pharmaceuticals USA Inc. 200 4000 MCG / 4 ML
63323-0318-01 Granisetron Fresenius Kabi USA, LLC 10 1000 MCG / 1 ML
67457-0863-01 Granisetron Hydrochloride Mylan Institutional LLC 10 1000 MCG / 1 ML
67457-0864-04 Granisetron Hydrochloride Mylan Institutional LLC 40 1000 MCG / 1 ML
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GRANISETRON HCL Pricing & Reimbursement

J1626 Private Payer Reimbursement
$0.39 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

GRANISETRON HCL Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 7.89%
Avg. Days to File 7.7days
Avg. Days to Pay 22.4days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J1626 claims analytics on FocalPoint →
OnPoint Oncology

GRANISETRON HCL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96374 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug Login for More
Not on the CMS JW / JZ list

CMS does not include Granisetron HCL (J1626) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1626. Wastage billing guide →

GRANISETRON HCL Medically Unlikely Edits (MUE)

The most billing units of J1626 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 100 mcg.

Practitioner Office & Hospital Outpatient
30 units / day
= 3,000 mcg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mcg Enter a dose to see how many billing units it is and whether it is under the limit.

GRANISETRON HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chemotherapy-Induced Nausea and Vomiting Postoperative Nausea and Vomiting
Drug Class
Serotonin 3 Receptor Antagonists [MoA]Serotonin-3 Receptor Antagonist [EPC]

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Frequently Asked Questions

Is there an available Granisetron Hcl billing and coding guide?
We have not yet identified a manufacturer source of Granisetron Hcl billing and coding information.
Are there any available Granisetron Hcl patient assistance programs?
Our team did not identify a source for Granisetron Hcl patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Granisetron Hcl prescribing information?
GRANISETRON HCL prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Granisetron Hcl side effect information?
Our team has not yet identified a source of side effects information for GRANISETRON HCL. Please check back in a few weeks.
Does billing GRANISETRON HCL require JZ/JW wastage modifiers?
CMS does not include GRANISETRON HCL (J1626) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1626. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to GRANISETRON HCL.

Q0166Granisetron HClGranisetron hydrochloride, 1 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at the time of chemotherapy treatment, not to exceed a 24 hour dosage regimenBreckenridgeAdded April 1, 1998J2469PalonosetronInjection, palonosetron hcl, 25 mcgMultiple ManufacturersAdded January 1, 2005Q0162OndansetronOndansetron 1 mg, oral, fda approved prescription anti-emetic, for use as a complete therapeutic substitute for an iv anti-emetic at the time of chemotherapy treatment, not to exceed a 48 hour dosage regimenMultiple ManufacturersAdded January 1, 2012J2765METOCLOPRAMIDE HCLInjection, metoclopramide hcl, up to 10 mgMultiple ManufacturersAdded January 1, 1982J3250TIGANInjection, trimethobenzamide hcl, up to 200 mgPar Pharmaceutical, IncAdded January 1, 1982J8501APREPITANTAprepitant, oral, 5 mgMultiple ManufacturersAdded January 1, 2005J1454AKYNZEOInjection, fosnetupitant 235 mg and palonosetron 0.25 mgHelsinn Therapeutics USAdded January 1, 2019J1627SUSTOLInjection, granisetron, extended-release, 0.1 mgHeron TherapeuticsAdded January 1, 2018J2405ONDANSETRON HCLInjection, ondansetron hydrochloride, per 1 mgMultiple ManufacturersAdded January 1, 1993J2468POSFREAInjection, palonosetron hydrochloride (posfrea), 25 microgramsAvyxa PharmaAdded July 1, 2024