Aponvie J Code: J8502

Drug & Product Overview

HCPCS Descriptor Injection, aprepitant (aponvie), 1 mg

HCPCS Added Date April 1, 2026

Manufacturer Heron Therapeutics

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Emulsion

About Aponvie

Aponvie is a medication aligned to the HCPCS J Code: J8502 for billing, pricing, and reimbursement purposes in the United States. This Anti-Emetic medication is administered via the intravenous route and manufactured by Heron Therapeutics.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 1 of 2 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
47426-0401-10	Aponvie	Heron Therapeutics, Inc.	320	32 MG / 4.4 ML
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Aponvie Pricing & Reimbursement

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Aprepitant 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J0185	Heron Therapeutics	Aprepitant	Injection, aprepitant, 1 mg
J8502	Heron Therapeutics	Aprepitant	Injection, aprepitant (aponvie), 1 mg

Aponvie CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

Aponvie Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

postoperative nausea and vomiting (PONV)

Drug Class

Cytochrome P450 2C9 Inducers [MoA]Cytochrome P450 3A4 Inducers [MoA]Cytochrome P450 3A4 Inhibitors [MoA]Neurokinin 1 Antagonists [MoA]Substance P/Neurokinin-1 Receptor Antagonist [EPC]

Frequently Asked Questions

Is there an available Aponvie billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for Aponvie.

Are there any available Aponvie patient assistance programs?

Aponvie patient assistance information can be found through Heron Therapeutics. Visit Here →

Where can I find Aponvie prescribing information?

Aponvie prescribing information can be found at the link below. Visit Here →

Where can I find Aponvie side effect information?

Our team has not yet identified a source of side effects information for Aponvie.

Does billing Aponvie require JZ/JW wastage modifiers?

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.