EMEND J Code: J1453

Drug & Product Overview

HCPCS Descriptor Injection, fosaprepitant, 1 mg

HCPCS Added Date January 1, 2009

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution | Not Available

About EMEND

Emend is a medication aligned to the HCPCS J Code: J1453 for billing, pricing, and reimbursement purposes in the United States. It is an Anti-Emetic drug administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Fosaprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Fosaprepitant works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting. This medication will not treat nausea or vomiting that has already started. Ask your doctor what you should do if you already have nausea or vomiting.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 25 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00006-3061-00	Emend	Merck Sharp & Dohme LLC	150	150 MG / 5 ML
00143-9384-01	Fosaprepitant Dimeglumine	Hikma Pharmaceuticals USA Inc.	150	150 MG / 5 ML
16714-0248-01	Fosaprepitant	NorthStar RxLLC	150	150 MG / 5 ML
43598-0859-11	Fosaprepitant	Dr. Reddy's Laboratories Inc.,	150	150 MG / 5 ML
55150-0299-01	Fosaprepitant Dimeglumine	Eugia US LLC	150	150 MG / 5 ML
•••••-••••-•• Log in to view	EMEND
	EMEND
	EMEND

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EMEND Pricing & Reimbursement

J1453 Private Payer Reimbursement

$0.34 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Fosaprepitant 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J1434	Amneal Biosciences	Fosaprepitant	Injection, fosaprepitant (focinvez), 1 mg
J1453	Generic Code (Multiple Manufacturers)	Fosaprepitant	Injection, fosaprepitant, 1 mg
J1456	Actavis Pharma	Fosaprepitant	Injection, fosaprepitant (teva), not therapeutically equivalent to j1453, 1 mg

EMEND CPT Administration Codes

CPT Code	Description
96375	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); each additional sequential intravenous push of a new substance/drug.

Not on the CMS JW / JZ list

CMS does not include Emend (J1453) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1453. Wastage billing guide →

EMEND Medically Unlikely Edits (MUE)

The most billing units of J1453 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

150 units / day

= 150 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

EMEND Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC) Nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC), including high-dose cisplatin Nausea and vomiting associated with highly or moderately emetogenic cancer chemotherapy Nausea and vomiting associated with highly or moderately emetogenic cancer chemotherapy (HEC or MEC) Nausea and vomiting associated with highly or moderately emetogenic cancer chemotherapy (single or multi-day regimens) Nausea and vomiting associated with highly or moderately emetogenic cancer chemotherapy (single-day regimens) Nausea and vomiting associated with moderately emetogenic cancer chemotherapy (MEC) nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC) nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC) or moderately emetogenic cancer chemotherapy (MEC) nausea and vomiting associated with moderately emetogenic cancer chemotherapy (MEC)

Drug Class

Cytochrome P450 2C9 Inducers [MoA]Cytochrome P450 3A4 Inducers [MoA]Cytochrome P450 3A4 Inhibitors [MoA]Neurokinin 1 Antagonists [MoA]Substance P/Neurokinin-1 Receptor Antagonist [EPC]

Frequently Asked Questions

Is there an available Emend billing and coding guide?

We have not yet identified a manufacturer source of Emend billing and coding information.

Are there any available Emend patient assistance programs?

Our team did not identify a source for Emend patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Emend prescribing information?

EMEND prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Emend side effect information?

Our team has not yet identified a source of side effects information for EMEND. Please check back in a few weeks.

Does billing EMEND require JZ/JW wastage modifiers?

CMS does not include EMEND (J1453) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1453. For more information, visit the link below.

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