CINVANTI J Code: J0185

Drug & Product Overview

HCPCS Descriptor Injection, aprepitant, 1 mg

HCPCS Added Date January 1, 2019

Manufacturer Heron Therapeutics

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Emulsion

About CINVANTI

Cinvanti is a medication aligned to the HCPCS J Code: J0185 for billing, pricing, and reimbursement purposes in the United States. Classified under Anti-Emetic, it is administered via the intravenous route and manufactured by Heron Therapeutics.

According to CMS Drug Use Information: Aprepitant is used to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) or surgery. It works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
47426-0201-01	Cinvanti	Heron Therapeutics, Inc.	130	130 MG / 18 ML

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CINVANTI Pricing & Reimbursement

J0185 Private Payer Reimbursement

$1.53 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Aprepitant 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J0185	Heron Therapeutics	Aprepitant	Injection, aprepitant, 1 mg
J8502	Heron Therapeutics	Aprepitant	Injection, aprepitant (aponvie), 1 mg

CINVANTI Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 11.17%

Avg. Days to File 9.8days

Avg. Days to Pay 24.3days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J0185 claims analytics on FocalPoint →

CINVANTI CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Cinvanti (J0185) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0185. Wastage billing guide →

CINVANTI Medically Unlikely Edits (MUE)

The most billing units of J0185 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

130 units / day

= 130 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

CINVANTI Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

delayed nausea and vomiting associated with moderately emetogenic cancer chemotherapy (MEC) nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC) nausea and vomiting associated with moderately emetogenic cancer chemotherapy (MEC)

Drug Class

Cytochrome P450 2C9 Inducers [MoA]Cytochrome P450 3A4 Inducers [MoA]Cytochrome P450 3A4 Inhibitors [MoA]Neurokinin 1 Antagonists [MoA]Substance P/Neurokinin-1 Receptor Antagonist [EPC]

Frequently Asked Questions

Is there an available Cinvanti billing and coding guide?

Billing and coding information for CINVANTI can be found through Heron Therapeutics. Visit Here →

Are there any available Cinvanti patient assistance programs?

CINVANTI patient assistance information can be found through Heron Therapeutics. Visit Here →

Where can I find Cinvanti prescribing information?

CINVANTI prescribing information can be found at the link below: Visit Here →

Where can I find Cinvanti side effect information?

Information regarding CINVANTI's side effects can be found at MedlinePlus Visit Here →

Does billing CINVANTI require JZ/JW wastage modifiers?

CMS does not include CINVANTI (J0185) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0185. For more information, visit the link below.

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