Fosaprepitant J Code: J1456

Drug & Product Overview

HCPCS Descriptor Injection, fosaprepitant (teva), not therapeutically equivalent to j1453, 1 mg

HCPCS Added Date January 1, 2023

Manufacturer Teva

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About Fosaprepitant

Fosaprepitant is a medication aligned to the HCPCS J Code: J1456 for billing, pricing, and reimbursement purposes in the United States. It is an Anti-Emetic drug administered via the intravenous route and manufactured by Teva.

According to CMS Drug Use Information: Fosaprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Fosaprepitant works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting. This medication will not treat nausea or vomiting that has already started. Ask your doctor what you should do if you already have nausea or vomiting.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00591-4385-79	Fosaprepitant	Actavis Pharma, Inc.	150	150 MG

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Fosaprepitant Pricing & Reimbursement

J1456 Private Payer Reimbursement

$0.90 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Fosaprepitant 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J1434	Amneal Pharmaceuticals	Fosaprepitant	Injection, fosaprepitant (focinvez), 1 mg
J1453	Generic Code (Multiple Manufacturers)	Fosaprepitant	Injection, fosaprepitant, 1 mg
J1456	Teva	Fosaprepitant	Injection, fosaprepitant (teva), not therapeutically equivalent to j1453, 1 mg

Fosaprepitant CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Fosaprepitant (J1456) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1456. Wastage billing guide →

Fosaprepitant Medically Unlikely Edits (MUE)

The most billing units of J1456 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

150 units / day

= 150 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Fosaprepitant Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC) nausea and vomiting associated with moderately emetogenic cancer chemotherapy (MEC)

Drug Class

Cytochrome P450 2C9 Inducers [MoA]Cytochrome P450 3A4 Inducers [MoA]Cytochrome P450 3A4 Inhibitors [MoA]Neurokinin 1 Antagonists [MoA]Substance P/Neurokinin-1 Receptor Antagonist [EPC]

Frequently Asked Questions

Is there an available Fosaprepitant billing and coding guide?

We have not yet identified a manufacturer source of Fosaprepitant billing and coding information.

Are there any available Fosaprepitant patient assistance programs?

Our team did not identify a source for Fosaprepitant patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Fosaprepitant prescribing information?

Fosaprepitant prescribing information can be found at the link below: Visit Here →

Where can I find Fosaprepitant side effect information?

Information regarding Fosaprepitant's side effects can be found at MedlinePlus Visit Here →

Does billing Fosaprepitant require JZ/JW wastage modifiers?

CMS does not include Fosaprepitant (J1456) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1456. For more information, visit the link below.

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