ALYGLO J Code: J1552
Injection, immune globulin (alyglo), 500 mg
Q4 2026 Medicare Payment Limit for J1552, effective October 1, 2026: $120.04 per HCPCS billing unit, down 1.2% from $121.544. From CMS's final file.
Drug & Product Overview
About ALYGLO
Alyglo is a medication aligned to the HCPCS J Code: J1552 for billing, pricing, and reimbursement purposes in the United States. It is a Hematology drug administered via the intravenous route and manufactured by GC Biopharma.
According to CMS Drug Use Information: This medication is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system. This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP). Platelets are needed to stop bleeding and form blood clots. Some immune globulin products may also be used to treat certain types of muscle weakness problem (multifocal motor neuropathy, dermatomyositis) or a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP). Some products may also be used to prevent certain blood vessel disorders in people with Kawasaki syndrome.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 3 of 6 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 61476-0104-05 | Alyglo | GC Biopharma Corp. | 10 | 5000 MG / 50 ML |
| 61476-0104-10 | Alyglo | GC Biopharma Corp. | 20 | 10000 MG / 100 ML |
| 61476-0104-20 | Alyglo | GC Biopharma Corp. | 40 | 20000 MG / 200 ML |
| •••••-••••-•• Log in to view | ALYGLO | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | ALYGLO | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | ALYGLO | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
ALYGLO Pricing & Reimbursement
National median reimbursement across major commercial payers.
Create an account on PayerPrice for more information →
Historical Graphing and Billing Calculator
Log in to calculate billing and reimbursement with live ASP, WAC & AWP pricing.
Login to use the calculator →Immune Globulin 505(b)(2) Information:
| HCPCS Code | Manufacturer | Active Ingredient | HCPCS Description |
|---|---|---|---|
| J1552 | GC Biopharma | Immune Globulin | Injection, immune globulin (alyglo), 500 mg |
| J1566 | Takeda Pharmaceuticals | Immune Globulin | Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mg |
| J1576 | Generic Code (Multiple Manufacturers) | Immune Globulin | Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mg |
ALYGLO CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96365 | Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour |
| 96366 | Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure) |
This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →
ALYGLO Medically Unlikely Edits (MUE)
The most billing units of J1552 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
ALYGLO Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
Login for BuyandBill.com Analytics
Unlock deeper insights with BuyandBill’s Comparative Report!
- Compare ASP, WAC, and AWP across drugs.
- Visualize Drug Price Movement Over Time
- Tailor reports to drug class, manufacturer, or HCPCS Code.
- Compare Biosimilar and 505(b)(2) products.
Frequently Asked Questions
Is there an available ALYGLO billing and coding guide?
What are the available ALYGLO patient assistance programs?
Where can I find ALYGLO prescribing information?
Where can I find ALYGLO side effect information?
Does billing ALYGLO require JZ/JW wastage modifiers?
About BuyandBill.com:
The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.
Related Drug Codes
Explore billing, coding, and pricing for drugs related to ALYGLO.
