Home › Drug Codes › J Codes › J1554 · ASCENIV
Updated July 1st, 2026

ASCENIV J Code: J1554

Injection, immune globulin (asceniv), 500 mg

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Q4 2026 Medicare Payment Limit for J1554, effective October 1, 2026: $508.454 per HCPCS billing unit, down 0.1% from $509.139. From CMS's final file.

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Medicare Payment Limit ?
$509.139
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$509.139
/ HCPCS billing unit · APC 9392
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, immune globulin (asceniv), 500 mg
HCPCS Added Date April 1, 2021
Manufacturer Adma Biologics
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Liquid

About ASCENIV

Asceniv is a medication aligned to the HCPCS J Code: J1554 for billing, pricing, and reimbursement purposes in the United States. This Immunoglobulin medication is administered via the intravenous route and manufactured by Adma Biologics.

According to CMS Drug Use Information: This medication is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system. This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP). Platelets are needed to stop bleeding and form blood clots. Some immune globulin products may also be used to treat certain types of muscle weakness problem (multifocal motor neuropathy, dermatomyositis) or a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP). Some products may also be used to prevent certain blood vessel disorders in people with Kawasaki syndrome.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
69800-0250-01 Asceniv ADMA Biologics, Inc. 10 5000 MG / 50 ML
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ASCENIV Pricing & Reimbursement

J1554 Private Payer Reimbursement
$511.30 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

ASCENIV Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 7.51%
Avg. Days to File 3.6days
Avg. Days to Pay 21.1days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J1554 claims analytics on FocalPoint →
OnPoint Oncology

ASCENIV CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Asceniv (J1554) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ASCENIV Medically Unlikely Edits (MUE)

The most billing units of J1554 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg.

Practitioner Office & Hospital Outpatient
240 units / day
= 120,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

ASCENIV Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Measles post-exposure prophylaxis Measles pre-exposure prophylaxis Primary humoral immunodeficiency (PI)
Drug Class
Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

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Frequently Asked Questions

Is there an available Asceniv billing and coding guide?
Billing and coding information for ASCENIV can be found through Adma Biologics. Visit Here →
Are there any available Asceniv patient assistance programs?
ASCENIV patient assistance information can be found through Adma Biologics. Visit Here →
Where can I find Asceniv prescribing information?
ASCENIV prescribing information can be found at the link below: Visit Here →
Where can I find Asceniv side effect information?
Our team has not yet identified a source of side effects information for ASCENIV. Please check back in a few weeks.
Does billing ASCENIV require JZ/JW wastage modifiers?
CMS has identified ASCENIV(J1554) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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