Home › Drug Codes › J Codes › J1555 · CUVITRU
Updated July 1st, 2026

CUVITRU J Code: J1555

Injection, immune globulin (cuvitru), 100 mg

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Q4 2026 Medicare Payment Limit for J1555, effective October 1, 2026: $17.994 per HCPCS billing unit, down 0.8% from $18.147. From CMS's final file.

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Medicare Payment Limit ?
$18.147
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$18.147
/ HCPCS billing unit · APC 9034
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
6
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Drug & Product Overview

HCPCS Descriptor Injection, immune globulin (cuvitru), 100 mg
HCPCS Added Date January 1, 2018
Manufacturer Takeda Pharmaceuticals
Route of Administration Subcutaneous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection, Solution

About CUVITRU

Cuvitru is a medication aligned to the HCPCS J Code: J1555 for billing, pricing, and reimbursement purposes in the United States. It is an Immunoglobulin drug administered via the subcutaneous route and manufactured by Takeda Pharmaceuticals.

According to CMS Drug Use Information: This medication is used to boost the body's natural defense system against infection in persons with a weakened immune system (primary immune deficiency). Immune globulin contains natural substances called antibodies (a type called IgG) that come from healthy human blood (plasma). These antibodies help protect your body against infections and help you to fight an infection if you get sick. Some immune globulin products may also be used to treat a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 6 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00944-2850-01 Cuvitru Takeda Pharmaceuticals America, Inc. 10 1000 MG / 5 ML
00944-2850-03 Cuvitru Takeda Pharmaceuticals America, Inc. 20 2000 MG / 10 ML
00944-2850-05 Cuvitru Takeda Pharmaceuticals America, Inc. 40 4000 MG / 20 ML
00944-2850-07 Cuvitru Takeda Pharmaceuticals America, Inc. 80 8000 MG / 40 ML
00944-2850-09 Cuvitru Takeda Pharmaceuticals America, Inc. 100 10000 MG / 50 ML
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CUVITRU Pricing & Reimbursement

J1555 Private Payer Reimbursement
$17.73 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

CUVITRU CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96369 Subcutaneous infusion for therapy or prophylaxis (specify substance or drug); initial, up to 1 hour, including pump set-up and establishment of subcutaneous infusion site(s)
96370 Subcutaneous infusion for therapy or prophylaxis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96371 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); subcutaneous or intramuscular. Login for More
JW / JZ modifiers apply

CMS has identified Cuvitru (J1555) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

CUVITRU Medically Unlikely Edits (MUE)

The most billing units of J1555 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 100 mg.

Practitioner Office & Hospital Outpatient
480 units / day
= 48,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

CUVITRU Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Primary Humoral Immunodeficiency (PI)
Drug Class
Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

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Frequently Asked Questions

Is there an available Cuvitru billing and coding guide?
Billing and coding information for CUVITRU can be found through Takeda Pharmaceuticals. Visit Here →
Are there any available Cuvitru patient assistance programs?
CUVITRU patient assistance information can be found through Takeda. Visit Here →
Where can I find Cuvitru prescribing information?
CUVITRU prescribing information can be found at the link below: Visit Here →
Where can I find Cuvitru side effect information?
Our team has not yet identified a source of side effects information for CUVITRU. Please check back in a few weeks.
Does billing CUVITRU require JZ/JW wastage modifiers?
CMS has identified CUVITRU(J1555) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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