Home › Drug Codes › J Codes › J1459 · PRIVIGEN
Updated July 1st, 2026

PRIVIGEN J Code: J1459

Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mg

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Q4 2026 Medicare Payment Limit for J1459, effective October 1, 2026: $48.963 per HCPCS billing unit, down 4.4% from $51.218. From CMS's final file.

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Medicare Payment Limit ?
$51.218
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$51.218
/ HCPCS billing unit · APC 1214
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
4
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Drug & Product Overview

HCPCS Descriptor Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mg
HCPCS Added Date January 1, 2009
Manufacturer CSL Behring
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Form Liquid

About PRIVIGEN

Privigen is a medication aligned to the HCPCS J Code: J1459 for billing, pricing, and reimbursement purposes in the United States. It is an Immunoglobulin drug administered via the intravenous route and manufactured by CSL Behring.

According to CMS Drug Use Information: This medication is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system. This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP). Platelets are needed to stop bleeding and form blood clots. Some immune globulin products may also be used to treat certain types of muscle weakness problem (multifocal motor neuropathy, dermatomyositis) or a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP). Some products may also be used to prevent certain blood vessel disorders in people with Kawasaki syndrome.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
44206-0436-05 Privigen CSL Behring AG 10 5000 MG / 50 ML
44206-0437-10 Privigen CSL Behring AG 20 10000 MG / 100 ML
44206-0438-20 Privigen CSL Behring AG 40 20000 MG / 200 ML
44206-0439-40 Privigen CSL Behring AG 80 40000 MG / 400 ML
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PRIVIGEN Pricing & Reimbursement

J1459 Private Payer Reimbursement
$52.31 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

PRIVIGEN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Privigen (J1459) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

PRIVIGEN Medically Unlikely Edits (MUE)

The most billing units of J1459 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg.

Practitioner Office & Hospital Outpatient
300 units / day
= 150,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

PRIVIGEN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chronic Immune Thrombocytopenic Purpura Chronic Inflammatory Demyelinating Polyneuropathy Primary Humoral Immunodeficiency
Drug Class
Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

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Frequently Asked Questions

Is there an available Privigen billing and coding guide?
Billing and coding information for PRIVIGEN can be found through CSL Behring. Visit Here →
Are there any available Privigen patient assistance programs?
PRIVIGEN patient assistance information can be found through CSL Behring. Visit Here →
Where can I find Privigen prescribing information?
PRIVIGEN prescribing information can be found at the link below: Visit Here →
Where can I find Privigen side effect information?
Our team has not yet identified a source of side effects information for PRIVIGEN. Please check back in a few weeks.
Does billing PRIVIGEN require JZ/JW wastage modifiers?
CMS has identified PRIVIGEN(J1459) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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J1557GAMMAPLEXInjection, immune globulin, (gammaplex), intravenous, non-lyophilized (e.g., liquid), 500 mgBio Products LaboratoryAdded January 1, 2012J1577QivigyInjection, immune globulin (qivigy), 100 mgKedrion BiopharmaAdded July 1, 2026J1554ASCENIVInjection, immune globulin (asceniv), 500 mgAdma BiologicsAdded April 1, 2021J1559HIZENTRAInjection, immune globulin (hizentra), 100 mgCSL BehringAdded January 1, 2011J1552ALYGLOInjection, immune globulin (alyglo), 500 mgGC BiopharmaAdded January 1, 2025J1561GAMMAKEDInjection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mgGrifolsAdded January 1, 2008J1569GAMMAGARD LIQUIDInjection, immune globulin, (gammagard liquid/gammagard liquid erc), 500 mgTakeda PharmaceuticalsAdded January 1, 2008J1576PANZYGAInjection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mgOctapharmaAdded July 1, 2023J1599PANZYGAInjection, immune globulin, intravenous, non-lyophilized (e.g., liquid), not otherwise specified, 500 mgOctapharmaAdded January 1, 2011J1556BIVIGAMInjection, immune globulin (bivigam), 500 mgAdma BiologicsAdded January 1, 2014