Home › Drug Codes › J Codes › J1576 · PANZYGA
Updated October 1st, 2026

PANZYGA J Code: J1576

Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mg

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Medicare Payment Limit ?
$70.25
/ HCPCS billing unit
APC Payment Limit ?
$70.25
/ HCPCS billing unit · APC 9144
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
24
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Drug & Product Overview

HCPCS Descriptor Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mg
HCPCS Added Date July 1, 2023
Manufacturer Octapharma
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Solution

About PANZYGA

Panzyga is a medication aligned to the HCPCS J Code: J1576 for billing, pricing, and reimbursement purposes in the United States. It is an Immunoglobulin drug administered via the intravenous route and manufactured by Octapharma.

According to CMS Drug Use Information: This medication is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system. This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenia purpura-ITP). Platelets are needed to stop bleeding and form blood clots. Some immune globulin products may also be used to treat certain types of muscle weakness problem (multifocal motor neuropathy, dermatomyositis) or a certain nerve disorder (chronic inflammatory demyelinating polyneuropathy-CIDP). Some products may also be used to prevent certain blood vessel disorders in people with Kawasaki syndrome.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 24 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00069-1109-02 Panzyga Pfizer Laboratories Div Pfizer Inc 5 2500 MG / 25 ML
00069-1224-02 Panzyga Pfizer Laboratories Div Pfizer Inc 10 5000 MG / 50 ML
00069-1312-02 Panzyga Pfizer Laboratories Div Pfizer Inc 20 10000 MG / 100 ML
00069-1415-02 Panzyga Pfizer Laboratories Div Pfizer Inc 40 20000 MG / 200 ML
68982-0822-02 Panzyga Octapharma USA Inc 5 2500 MG / 25 ML
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PANZYGA Pricing & Reimbursement

J1576 Private Payer Reimbursement
$73.77 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q4 2026

Immune Globulin 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J1552 GC Biopharma Immune Globulin Injection, immune globulin (alyglo), 500 mg
J1566 Takeda Pharmaceuticals Immune Globulin Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mg
J1576 Generic Code (Multiple Manufacturers) Immune Globulin Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mg

PANZYGA Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 8.5%
Avg. Days to File 7.1days
Avg. Days to Pay 23.4days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J1576 claims analytics on FocalPoint →
OnPoint Oncology

PANZYGA CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Panzyga (J1576) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

PANZYGA Medically Unlikely Edits (MUE)

The most billing units of J1576 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg.

Practitioner Office & Hospital Outpatient
600 units / day
= 300,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

PANZYGA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chronic Immune Thrombocytopenia Chronic Immune Thrombocytopenia (ITP) Chronic Inflammatory Demyelinating Polyneuropathy Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Primary Humoral Immunodeficiency Primary Humoral Immunodeficiency Diseases (PI)
Drug Class
Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

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Frequently Asked Questions

Is there an available Panzyga billing and coding guide?
Billing and coding information for PANZYGA can be found through Octapharma. Visit Here →
Are there any available Panzyga patient assistance programs?
PANZYGA patient assistance information can be found through Octapharma. Visit Here →
Where can I find Panzyga prescribing information?
PANZYGA prescribing information can be found at the link below: Visit Here →
Where can I find Panzyga side effect information?
Our team has not yet identified a source of side effects information for PANZYGA. Please check back in a few weeks.
Does billing PANZYGA require JZ/JW wastage modifiers?
CMS has identified PANZYGA(J1576) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to PANZYGA.

J1599PANZYGAInjection, immune globulin, intravenous, non-lyophilized (e.g., liquid), not otherwise specified, 500 mgOctapharmaAdded January 1, 2011J1566GAMMAGARD S-DInjection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mgTakeda PharmaceuticalsAdded January 1, 2006J1561GAMMAKEDInjection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mgGrifolsAdded January 1, 2008J1459PRIVIGENInjection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mgCSL BehringAdded January 1, 2009J1569GAMMAGARD LIQUIDInjection, immune globulin, (gammagard liquid/gammagard liquid erc), 500 mgTakeda PharmaceuticalsAdded January 1, 2008J1556BIVIGAMInjection, immune globulin (bivigam), 500 mgAdma BiologicsAdded January 1, 2014J1557GAMMAPLEXInjection, immune globulin, (gammaplex), intravenous, non-lyophilized (e.g., liquid), 500 mgBio Products LaboratoryAdded January 1, 2012J1559HIZENTRAInjection, immune globulin (hizentra), 100 mgCSL BehringAdded January 1, 2011J1568OCTAGAMInjection, immune globulin, (octagam), intravenous, non-lyophilized (e.g., liquid), 500 mgPfizerAdded January 1, 2008J1577QivigyInjection, immune globulin (qivigy), 100 mgKedrion BiopharmaAdded July 1, 2026