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Updated July 1st, 2026

BICILLIN L-A J Code: J0561

Injection, penicillin g benzathine, 100,000 units

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Q4 2026 Medicare Payment Limit for J0561, effective October 1, 2026: $25.612 per HCPCS billing unit, down 21.4% from $32.592. From CMS's final file.

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Medicare Payment Limit ?
$32.592
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$32.592
/ HCPCS billing unit · APC 1829
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
6
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Drug & Product Overview

HCPCS Descriptor Injection, penicillin g benzathine, 100,000 units
HCPCS Added Date January 1, 2011
Manufacturer Pfizer
Route of Administration Intramuscular
Generic Status Single-Source; Branded
Dosage Form Injection, Suspension

About BICILLIN L-A

Bicillin L-A is a medication aligned to the HCPCS J Code: J0561 for billing, pricing, and reimbursement purposes in the United States. This Antibiotic medication is administered via the intramuscular route and manufactured by Pfizer.

According to CMS Drug Use Information: Penicillin G benzathine is used to treat a wide variety of bacterial infections. It may also be used to prevent certain bacterial infections (such as rheumatic fever). This medication is a long-acting penicillin antibiotic. It works by stopping the growth of bacteria.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 6 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
50090-1016-00 Bicillin L-A A-S Medication Solutions 120 Bicillin L-A Intramusc ular Injection 1… Login for More
50090-1016-01 Bicillin L-A A-S Medication Solutions 12 Bicillin L-A Intramusc ular Injection 1… Login for More
60793-0700-10 Bicillin L-A Pfizer Laboratories Div Pfizer Inc 60 Bicillin L-A Intramusc ular Injection 6… Login for More
60793-0701-10 Bicillin L-A Pfizer Laboratories Div Pfizer Inc 120 Bicillin L-A Intramusc ular Injection 1… Login for More
60793-0702-10 Bicillin L-A Pfizer Laboratories Div Pfizer Inc 240 Bicillin L-A Intramusc ular Injection 2… Login for More
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BICILLIN L-A Pricing & Reimbursement

J0561 Private Payer Reimbursement
$31.92 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

BICILLIN L-A CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
JW / JZ modifiers apply

CMS has identified Bicillin L-A (J0561) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

BICILLIN L-A Medically Unlikely Edits (MUE)

The most billing units of J0561 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 100,000 units.

Practitioner Office & Hospital Outpatient
24 units / day
= 2,400 ,000 units per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

,000 units Enter a dose to see how many billing units it is and whether it is under the limit.

BICILLIN L-A Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Rheumatic fever and glomerulonephritis prophylaxis Streptococcal (Group A) Upper Respiratory Infections Syphilis Yaws, Bejel, and Pinta
Drug Class
Penicillin-class Antibacterial [EPC]Penicillins [CS]

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Frequently Asked Questions

Is there an available Bicillin L-A billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for BICILLIN L-A.
Are there any available Bicillin L-A patient assistance programs?
BICILLIN L-A patient assistance information can be found through Pfizer. Visit Here →
Where can I find Bicillin L-A prescribing information?
BICILLIN L-A prescribing information can be found at the link below: Visit Here →
Where can I find Bicillin L-A side effect information?
Information regarding BICILLIN L-A's side effects can be found at MedlinePlus Visit Here →
Does billing BICILLIN L-A require JZ/JW wastage modifiers?
CMS has identified BICILLIN L-A(J0561) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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