Home Drug Codes J Codes J3370 · VANCOMYCIN
Updated July 1st, 2026

VANCOMYCIN J Code: J3370

Injection, vancomycin hcl, 500 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
115
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Drug & Product Overview

HCPCS Descriptor Injection, vancomycin hcl, 500 mg
HCPCS Added Date January 1, 1986
Manufacturer Multiple Manufacturers
Route of Administration Intravenous, Intravitreal, Oral
Generic Status HCPCS Discontinued
Dosage Type Single-Dose
Dosage Form Injection, Powder, For Solution | Injection, Powder, Lyophilized, For Solution | Injection, Solution | Not Available

About VANCOMYCIN

Vancomycin is a medication aligned to the HCPCS J Code: J3370 for billing, pricing, and reimbursement purposes in the United States. It is an Antibiotic drug administered via the intravenous, intravitreal, or oral routes and manufactured by multiple companies.

According to CMS Drug Use Information: Vancomycin is used to treat serious bacterial infections. It is an antibiotic that works by stopping the growth of bacteria.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

115 NDC packages are crosswalked to J3370. Package detail is available to logged-in subscribers.

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VANCOMYCIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Vancomycin (J3370) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3370. Wastage billing guide →

VANCOMYCIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Antibiotic-associated pseudomembranous colitis caused by C. difficile Antibiotic-associated pseudomembranous colitis caused by C. difficile and staphylococcal enterocolitis Antibiotic-associated pseudomembranous colitis caused by C. difficile; staphylococcal enterocolitis Bone Infection Bone Infections Clostridioides difficile-Associated Diarrhea Enterocolitis Caused by S. aureus Enterocolitis caused by Staphylococcus aureus Infective Endocarditis Lower Respiratory Tract Infections Septicemia Serious or severe infections caused by susceptible methicillin-resistant staphylococci and other susceptible organisms Serious or severe infections caused by susceptible staphylococci and other susceptible organisms Serious or severe infections caused by susceptible staphylococci and vancomycin-susceptible organisms Serious or severe infections caused by susceptible strains of methicillin-resistant staphylococci Serious or severe infections caused by susceptible strains of methicillin-resistant staphylococci and other susceptible organisms Skin and Skin Structure Infections Staphylococcal enterocolitis antibiotic-associated pseudomembranous colitis caused by C. difficile, staphylococcal enterocolitis serious or severe infections caused by susceptible staphylococci, staphylococcal endocarditis, septicemia, bone infections, lower respiratory tract infections, skin and skin structure infections, endocarditis caused by S. viridans or S. bovis, endocarditis caused by enterococci, diphtheroid endocarditis, prosthetic valve endocarditis
Drug Class
Glycopeptide Antibacterial [EPC]Glycopeptides [CS]

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Frequently Asked Questions

Is there an available Vancomycin billing and coding guide?
We have not yet identified a manufacturer source of Vancomycin billing and coding information.
Are there any available Vancomycin patient assistance programs?
Our team did not identify a source for Vancomycin patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Vancomycin prescribing information?
VANCOMYCIN prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Vancomycin side effect information?
Our team has not yet identified a source of side effects information for VANCOMYCIN. Please check back in a few weeks.
Does billing VANCOMYCIN require JZ/JW wastage modifiers?
CMS does not include VANCOMYCIN (J3370) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3370. For more information, visit the link below.

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