Home › Drug Codes › J Codes › J3373 · VANCOMYCIN HCL
Updated July 1st, 2026

VANCOMYCIN HCL J Code: J3373

Injection, vancomycin hydrochloride, 10 mg

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Q4 2026 Medicare Payment Limit for J3373, effective October 1, 2026: $0.032 per HCPCS billing unit, down 3.0% from $0.033. From CMS's final file.

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Medicare Payment Limit ?
$0.033
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
109
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Drug & Product Overview

HCPCS Descriptor Injection, vancomycin hydrochloride, 10 mg
HCPCS Added Date July 1, 2025
Manufacturer Multiple Manufacturers
Route of Administration Intravenous, Intravitreal
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection, Powder, For Solution | Injection, Powder, Lyophilized, For Solution | Injection, Solution | Not Available

About VANCOMYCIN HCL

Vancomycin HCL is a medication aligned to the HCPCS J Code: J3373 for billing, pricing, and reimbursement purposes in the United States. It is an Antibiotic drug administered via the intravenous or intravitreal routes and manufactured by multiple companies.

According to CMS Drug Use Information: Vancomycin is used to treat serious bacterial infections. It is an antibiotic that works by stopping the growth of bacteria.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 109 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00143-9355-10 Vancomycin Hydrochloride Hikma Pharmaceuticals USA Inc. 750 750 MG
00338-0122-04 Vancomycin Hydrochloride Baxter Healthcare Corporation 500 1250 MG / 250 ML
00409-1319-01 Vancomycin Hydrochloride Hospira, Inc. 1000 500 MG / 5 ML
00409-5017-01 Vancomycin HCl Pfizer Inc 1000 500 MG / 5 ML
16714-0309-10 Vancomycin HCl Northstar RxLLC 1000 Vancomycin HCl Intrave nous Solution Re… Login for More
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VANCOMYCIN HCL Pricing & Reimbursement

J3373 Private Payer Reimbursement
$0.03 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Vancomycin Hcl 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J3373 Generic Code (Multiple Manufacturers) Vancomycin Hcl Injection, vancomycin hydrochloride, 10 mg
J3374 Generic Code (Multiple Manufacturers) Vancomycin Hcl Injection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mg
J3375 Generic Code (Multiple Manufacturers) Vancomycin Hcl Injection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mg
J3376 Hikma Vancomycin Hcl Injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg

VANCOMYCIN HCL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

VANCOMYCIN HCL Medically Unlikely Edits (MUE)

The most billing units of J3373 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg.

Practitioner Office & Hospital Outpatient
600 units / day
= 6,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

VANCOMYCIN HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Antibiotic-associated pseudomembranous colitis caused by C. difficile Antibiotic-associated pseudomembranous colitis caused by C. difficile and staphylococcal enterocolitis Antibiotic-associated pseudomembranous colitis caused by C. difficile; staphylococcal enterocolitis Bone Infection Bone Infections Infective Endocarditis Lower Respiratory Tract Infections Septicemia Serious or severe infections caused by susceptible methicillin-resistant staphylococci and other susceptible organisms Serious or severe infections caused by susceptible staphylococci and other susceptible organisms Serious or severe infections caused by susceptible staphylococci and vancomycin-susceptible organisms Serious or severe infections caused by susceptible strains of methicillin-resistant staphylococci Serious or severe infections caused by susceptible strains of methicillin-resistant staphylococci and other susceptible organisms Skin and Skin Structure Infections Staphylococcal enterocolitis antibiotic-associated pseudomembranous colitis caused by C. difficile, staphylococcal enterocolitis serious or severe infections caused by susceptible staphylococci, staphylococcal endocarditis, septicemia, bone infections, lower respiratory tract infections, skin and skin structure infections, endocarditis caused by S. viridans or S. bovis, endocarditis caused by enterococci, diphtheroid endocarditis, prosthetic valve endocarditis
Drug Class
Glycopeptide Antibacterial [EPC]Glycopeptides [CS]

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Frequently Asked Questions

Is there an available VANCOMYCIN HCL billing and coding guide?
Our team has not identified a manufacturer-source of billing and coding information for VANCOMYCIN HCL. Please reach out to our team if this is a mistake.
Are there any available VANCOMYCIN HCL patient assistance programs?
Our team has not identified a source of patient assistance information for VANCOMYCIN HCL. Please reach out to us if this is a mistake.
Where can I find VANCOMYCIN HCL prescribing information?
VANCOMYCIN HCL prescribing information can be found at the link below. Visit Here →
Where can I find VANCOMYCIN HCL side effect information?
Side effect information for VANCOMYCIN HCL can be found through MedlinePlus. Visit Here →
Does billing VANCOMYCIN HCL require JZ/JW wastage modifiers?
CMS does not include VANCOMYCIN HCL (J3373) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3373. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to VANCOMYCIN HCL.

J3374VANCOMYCIN HCLInjection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mgMultiple ManufacturersAdded July 1, 2025J3376VANCOMYCIN HCLInjection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mgHikmaAdded January 1, 2026J3370VANCOMYCINInjection, vancomycin hcl, 500 mgMultiple ManufacturersAdded January 1, 1986J3371Vancomycin HClInjection, vancomycin hcl (mylan), not therapeutically equivalent to j3370, 500 mgMylan PharmaceuticalsAdded January 1, 2023J3375VANCOMYCIN HCLInjection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mgHikmaAdded July 1, 2025J0694CEFOXITINInjection, cefoxitin sodium, 1 gmMultiple ManufacturersAdded January 1, 1992J0737CLINDAMYCIN PHOSPHATE IN NACLInjection, clindamycin phosphate (baxter), not therapeutically equivalent to j0736, 300 mgBaxter HealthcareAdded July 1, 2023J3260TOBRAMYCIN SULFATEInjection, tobramycin sulfate, up to 80 mgMultiple ManufacturersAdded January 1, 1982J0457AZTREONAMInjection, aztreonam, 100 mgMultiple ManufacturersAdded July 1, 2023J0525CEFOTETAN DISODIUMInjection, cefotetan disodium, 10 mgMultiple ManufacturersAdded October 1, 2025