Home › Drug Codes › J Codes › J3376 · VANCOMYCIN HCL
Updated July 1st, 2026

VANCOMYCIN HCL J Code: J3376

Injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg

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Q4 2026 Medicare Payment Limit for J3376, effective October 1, 2026: $0.016 per HCPCS billing unit, down 5.9% from $0.017. From CMS's final file.

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Medicare Payment Limit ?
$0.017
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
7
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Drug & Product Overview

HCPCS Descriptor Injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg
HCPCS Added Date January 1, 2026
Manufacturer Hikma
Route of Administration Intravenous, Oral
Generic Status Single-Source; Branded
Dosage Form Injection, Powder, For Solution

About VANCOMYCIN HCL

Vancomycin HCL is a medication aligned to the HCPCS J Code: J3376 for billing, pricing, and reimbursement purposes in the United States. It is an Antibiotic drug administered via the intravenous or oral routes and manufactured by Hikma.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 7 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00143-9161-10 Vancomycin Hydrochloride HIKMA PHARMACEUTICALS USA INC. 500 513 MG
00143-9161-25 Vancomycin Hydrochloride HIKMA PHARMACEUTICALS USA INC. 1250 513 MG
00143-9162-10 Vancomycin Hydrochloride HIKMA PHARMACEUTICALS USA INC. 1000 1025 MG
00143-9163-01 Vancomycin Hydrochloride HIKMA PHARMACEUTICALS USA INC. 500 Vancomycin Hydrochlori de Intravenous I… Login for More
00143-9164-01 Vancomycin Hydrochloride HIKMA PHARMACEUTICALS USA INC. 1000 Vancomycin Hydrochlori de Intravenous I… Login for More
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VANCOMYCIN HCL
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VANCOMYCIN HCL Pricing & Reimbursement

J3376 Private Payer Reimbursement
$0.02 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Vancomycin Hcl 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J3373 Generic Code (Multiple Manufacturers) Vancomycin Hcl Injection, vancomycin hydrochloride, 10 mg
J3374 Generic Code (Multiple Manufacturers) Vancomycin Hcl Injection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mg
J3375 Generic Code (Multiple Manufacturers) Vancomycin Hcl Injection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mg
J3376 Hikma Vancomycin Hcl Injection, vancomycin hcl (hikma), not therapeutically equivalent to j3373, 10 mg

VANCOMYCIN HCL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

VANCOMYCIN HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Bone Infections Clostridioides difficile-Associated Diarrhea Enterocolitis Caused by S. aureus Enterocolitis caused by Staphylococcus aureus Infective Endocarditis Lower Respiratory Tract Infections Septicemia Skin and Skin Structure Infections
Drug Class
Glycopeptide Antibacterial [EPC]Glycopeptides [CS]

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Frequently Asked Questions

Is there a manufacturer-published VANCOMYCIN HCL billing and coding guide?
We have not identified a manufacturer-published source of billing and coding information for VANCOMYCIN HCL. Please reach out to our team if you believe that this is a mistake.
Is there an available VANCOMYCIN HCL patient assistance program?
Our team did not identify a source of patient assistance information for VANCOMYCIN HCL. Please reach out if you believe that this is a mistake.
Where can I find VANCOMYCIN HCL prescribing information?
VANCOMYCIN HCL prescribing information can be found at the link below. Visit Here →
Where can I find VANCOMYCIN HCL side effect information?
VANCOMYCIN HCL side effect information can be found through MedlinePlus. Visit Here →
Does billing VANCOMYCIN HCL require JZ/JW wastage modifiers?
CMS does not include VANCOMYCIN HCL (J3376) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3376. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to VANCOMYCIN HCL.

J3373VANCOMYCIN HCLInjection, vancomycin hydrochloride, 10 mgMultiple ManufacturersAdded July 1, 2025J3374VANCOMYCIN HCLInjection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mgMultiple ManufacturersAdded July 1, 2025J3370VANCOMYCINInjection, vancomycin hcl, 500 mgMultiple ManufacturersAdded January 1, 1986J3371Vancomycin HClInjection, vancomycin hcl (mylan), not therapeutically equivalent to j3370, 500 mgMylan PharmaceuticalsAdded January 1, 2023J3375VANCOMYCIN HCLInjection, vancomycin hydrochloride (tyzavan), not therapeutically equivalent to j3373, 10 mgHikmaAdded July 1, 2025J0694CEFOXITINInjection, cefoxitin sodium, 1 gmMultiple ManufacturersAdded January 1, 1992J0737CLINDAMYCIN PHOSPHATE IN NACLInjection, clindamycin phosphate (baxter), not therapeutically equivalent to j0736, 300 mgBaxter HealthcareAdded July 1, 2023J3260TOBRAMYCIN SULFATEInjection, tobramycin sulfate, up to 80 mgMultiple ManufacturersAdded January 1, 1982J0457AZTREONAMInjection, aztreonam, 100 mgMultiple ManufacturersAdded July 1, 2023J0525CEFOTETAN DISODIUMInjection, cefotetan disodium, 10 mgMultiple ManufacturersAdded October 1, 2025