RIFAMPIN J Code: J2804

Drug & Product Overview

HCPCS Descriptor Injection, rifampin, 1 mg

HCPCS Added Date April 1, 2025

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Form Injection, Powder, Lyophilized, For Solution

About RIFAMPIN

Rifampin is a medication aligned to the HCPCS J Code: J2804 for billing, pricing, and reimbursement purposes in the United States. Classified under Antibiotic, it is administered via the intravenous route and manufactured by multiple companies.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00068-0597-01	Rifadin IV	Sanofi-Aventis U.S. LLC	600	600 MG / 10 ML
63323-0351-20	Rifampin	Fresenius Kabi USA, LLC	600	600 MG
67457-0445-60	Rifampin	Mylan Institutional LLC	600	600 MG / 10 ML

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RIFAMPIN Pricing & Reimbursement

J2804 Private Payer Reimbursement

$0.15 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Rifampin 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J2804	Generic Code (Multiple Manufacturers)	Rifampin	Injection, rifampin, 1 mg

RIFAMPIN CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

RIFAMPIN Medically Unlikely Edits (MUE)

The most billing units of J2804 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

1,200 units / day

= 1,200 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

RIFAMPIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Meningococcal Carrier State Meningococcal Carriers Tuberculosis

Drug Class

Rifamycin Antibacterial [EPC]Rifamycins [CS]

Frequently Asked Questions

Is there a manufacturer-published RIFAMPIN billing and coding guide?

Our team has not identified a manufacturer-published billing and coding guide for RIFAMPIN.

What are the available RIFAMPIN patient assistance programs?

Our team has not identified a source of patient assitsance information for RIFAMPIN.

Where can I find RIFAMPIN prescribing information?

RIFAMPIN prescribing information can be found at the link below. Visit Here →

Where can I find RIFAMPIN side effect information?

Side effect information for RIFAMPIN can be found at the following source.

Does billing RIFAMPIN require JZ/JW wastage modifiers?

CMS does not include RIFAMPIN (J2804) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2804. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.