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Updated July 1st, 2026

STREPTOMYCIN SULFATE J Code: J3000

Injection, streptomycin, up to 1 gm

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Q4 2026 Medicare Payment Limit for J3000, effective October 1, 2026: $16.407 per HCPCS billing unit, down 39.0% from $26.883. From CMS's final file.

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Medicare Payment Limit ?
$26.883
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, streptomycin, up to 1 gm
HCPCS Added Date January 1, 1982
Manufacturer XGen Pharmaceuticals DJB, Inc
Route of Administration Intramuscular
Generic Status Single-Source; Branded
Dosage Form Injection, Powder, Lyophilized, For Solution

About STREPTOMYCIN SULFATE

Streptomycin Sulfate is a medication aligned to the HCPCS J Code: J3000 for billing, pricing, and reimbursement purposes in the United States. This Antibiotic medication is administered via the intramuscular route and manufactured by XGen Pharmaceuticals DJB, Inc.

According to CMS Drug Use Information: This medication is used with other medications to treat active tuberculosis (TB) infection if you cannot take other drugs for TB or if you have a type of TB that cannot be treated with other drugs (drug-resistant TB). Streptomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by killing the organisms that cause the infection. This drug may also be used to treat other serious infections (such as Mycobacterium avium complex-MAC, tularemia, endocarditis, plague) along with other medications.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
39822-0706-02 Streptomycin XGen Pharmaceuticals DJB, Inc. 10 Streptomycin Intramusc ular Injection 1… Login for More
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STREPTOMYCIN SULFATE Pricing & Reimbursement

J3000 Private Payer Reimbursement
$34.36 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

STREPTOMYCIN SULFATE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
Not on the CMS JW / JZ list

CMS does not include Streptomycin Sulfate (J3000) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3000. Wastage billing guide →

STREPTOMYCIN SULFATE Medically Unlikely Edits (MUE)

The most billing units of J3000 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 gm.

Practitioner Office & Hospital Outpatient
2 units / day
= 2 gm per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

gm Enter a dose to see how many billing units it is and whether it is under the limit.

STREPTOMYCIN SULFATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Brucellosis Chancroid Enterococcal endocarditis Gram-negative bacillary bacteremia Granuloma inguinale (donovanosis) Meningitis Plague Pneumonia Streptococcal endocarditis Tuberculosis Tularemia Urinary tract infection
Drug Class
Aminoglycoside Antibacterial [EPC]Aminoglycosides [CS]Antimycobacterial [EPC]

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Frequently Asked Questions

Is there an available Streptomycin Sulfate billing and coding guide?
We have not yet identified a manufacturer source of Streptomycin Sulfate billing and coding information.
Are there any available Streptomycin Sulfate patient assistance programs?
Our team did not identify a source for Streptomycin Sulfate patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Streptomycin Sulfate prescribing information?
STREPTOMYCIN SULFATE prescribing information can be found at the link below: Visit Here →
Where can I find Streptomycin Sulfate side effect information?
Our team has not yet identified a source of side effects information for STREPTOMYCIN SULFATE. Please check back in a few weeks.
Does billing STREPTOMYCIN SULFATE require JZ/JW wastage modifiers?
CMS does not include STREPTOMYCIN SULFATE (J3000) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3000. For more information, visit the link below.

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