RELIZORB B Code: B4105

Drug & Product Overview

HCPCS Descriptor In-line cartridge containing digestive enzyme(s) for enteral feeding, each

HCPCS Added Date January 1, 2019

Manufacturer Alcresta Therapeutics

Generic Status Single-Source; Branded

About RELIZORB

Relizorb is a medication aligned to the HCPCS B Code: B4105 for billing, pricing, and reimbursement purposes in the United States. It is an Enzyme Replacement Therapy drug manufactured by Alcresta Therapeutics.

Manufacturers, reach out to us to add more information.

NDC Code Information

1 NDC package is crosswalked to B4105. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	RELIZORB

Login to view 1 NDC package View pricing, complete NDC-to-HCPCS alignments, and package details.

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RELIZORB Pricing & Reimbursement

B4105 Private Payer Reimbursement

$190.96 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Not on the CMS JW / JZ list

CMS does not include Relizorb (B4105) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing B4105. Wastage billing guide →

Frequently Asked Questions

Is there an available Relizorb billing and coding guide?

Billing and coding information for RELIZORB can be found through Alcresta Therapeutics. Visit Here →

Are there any available Relizorb patient assistance programs?

RELIZORB patient assistance information can be found through Alcresta Therapeutics. Visit Here →

Where can I find Relizorb prescribing information?

RELIZORB prescribing information can be found at the link below: Visit Here →

Where can I find Relizorb side effect information?

Our team has not yet identified a source of side effects information for RELIZORB. Please check back in a few weeks.

Does billing RELIZORB require JZ/JW wastage modifiers?

CMS does not include RELIZORB (B4105) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing B4105. For more information, visit the link below.

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