Home Drug Codes J Codes J0567 · BRINEURA
Updated July 1st, 2026

BRINEURA J Code: J0567

Injection, cerliponase alfa, 1 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
$123.379
/ HCPCS billing unit · APC 9014
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, cerliponase alfa, 1 mg
HCPCS Added Date January 1, 2019
Manufacturer Biomarin Pharmaceuticals
Route of Administration Multiple Routes
Generic Status Single-Source; Branded
Dosage Form Kit

About BRINEURA

Brineura is a medication aligned to the HCPCS J Code: J0567 for billing, pricing, and reimbursement purposes in the United States. This Enzyme Replacement Therapy medication is administered via the multiple routes route and manufactured by Biomarin Pharmaceuticals.

Manufacturers, reach out to us to add more information.

NDC Code Information

1 NDC package is crosswalked to J0567. Package detail is available to logged-in subscribers.

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BRINEURA Pricing & Reimbursement

J0567 Private Payer Reimbursement
$118.10 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

BRINEURA CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Brineura (J0567) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0567. Wastage billing guide →

BRINEURA Medically Unlikely Edits (MUE)

The most billing units of J0567 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
300 units / day
= 300 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

BRINEURA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Neuronal ceroid lipofuscinosis type 2 (CLN2 disease)

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Frequently Asked Questions

Is there an available Brineura billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for BRINEURA.
Are there any available Brineura patient assistance programs?
BRINEURA patient assistance information can be found through Biomarin Pharma. Visit Here →
Where can I find Brineura prescribing information?
BRINEURA prescribing information can be found at the link below: Visit Here →
Where can I find Brineura side effect information?
Our team has not yet identified a source of side effects information for BRINEURA. Please check back in a few weeks.
Does billing BRINEURA require JZ/JW wastage modifiers?
CMS does not include BRINEURA (J0567) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0567. For more information, visit the link below.

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