Home › Drug Codes › J Codes › J2355 · OPRELVEKIN
Updated October 1st, 2026

OPRELVEKIN J Code: J2355

Injection, oprelvekin, 5 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q4 2026
APC Payment Limit ?
Not published
CMS publishes none for Q4 2026
ASP ?
No current ASP
Not available for Q4 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
—
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Drug & Product Overview

HCPCS Descriptor Injection, oprelvekin, 5 mg
HCPCS Added Date January 1, 1999
Route of Administration Subcutaneous
Generic Status Single-Source; Branded

About OPRELVEKIN

Oprelvekin is a medication aligned to the HCPCS J Code: J2355 for billing, pricing, and reimbursement purposes in the United States. This Oncology Colony Stimulating Factor medication is administered via the subcutaneous route.

Manufacturers, reach out to us to add more information.

NDC Code Information

No NDC packages are aligned to J2355 in publicly available CMS files.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
No public NDC alignments
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OPRELVEKIN Pricing & Reimbursement

J2355 Private Payer Reimbursement
$474.44 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

OPRELVEKIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
Not on the CMS JW / JZ list

CMS does not include Oprelvekin (J2355) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2355. Wastage billing guide →

OPRELVEKIN Medically Unlikely Edits (MUE)

The most billing units of J2355 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 5 mg.

Practitioner Office & Hospital Outpatient
2 units / day
= 10 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

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Frequently Asked Questions

Is there an available oprelvekin billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for oprelvekin. Please reach out to us if this is a mistake.
Are there any available oprelvekin patient assistance programs?
Our team has not identified a source of patient assistance information for oprelvekin. Please reach out to us if this is a mistake.
Where can I find oprelvekin prescribing information?
No available source of prescribing information for oprelvekin
Where can I find oprelvekin side effect information?
A link for oprelvekin side effect information is not available.
Does billing oprelvekin require JZ/JW wastage modifiers?
CMS does not include OPRELVEKIN (J2355) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2355. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.