ROLVEDON J Code: J1449

Drug & Product Overview

HCPCS Descriptor Injection, eflapegrastim-xnst, 0.1 mg

HCPCS Added Date April 1, 2023

Manufacturer Assertio Pharmaceuticals

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Solution

About ROLVEDON

Rolvedon is a medication aligned to the HCPCS J Code: J1449 for billing, pricing, and reimbursement purposes in the United States. This Oncology Colony Stimulating Factor medication is administered via the subcutaneous route and manufactured by Assertio Pharmaceuticals.

According to CMS Drug Use Information: Eflapegrastim is a man-made version of a certain natural substance made by your body. It is used to help your body make more white blood cells. White blood cells are important to help you fight off infections. Eflapegrastim is given to people whose ability to make white blood cells is reduced due to chemotherapy.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
76961-0101-01	Rolvedon	Spectrum Pharmaceuticals, Inc.	132	13.2 MG / 0.6 ML
82497-0132-01	Rolvedon	Assertio Specialty Pharmaceuticals, LLC	132	13.2 MG / 0.6 ML

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ROLVEDON Pricing & Reimbursement

J1449 Private Payer Reimbursement

$24.08 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

ROLVEDON Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 10.45%

Avg. Days to File 6.5days

Avg. Days to Pay 20.9days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J1449 claims analytics on FocalPoint →

ROLVEDON CPT Administration Codes

CPT Code	Description
96401	Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic

JW / JZ modifiers apply

CMS has identified Rolvedon (J1449) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ROLVEDON Medically Unlikely Edits (MUE)

The most billing units of J1449 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

132 units / day

= 13.2 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ROLVEDON Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

non-myeloid malignancies with febrile neutropenia risk

Drug Class

Granulocyte Colony-Stimulating Factor [CS]Increased Myeloid Cell Production [PE]Leukocyte Growth Factor [EPC]

Frequently Asked Questions

Is there an available Rolvedon billing and coding guide?

Billing and coding information for ROLVEDON can be found through Assertio Pharmaceuticals. Visit Here →

Are there any available Rolvedon patient assistance programs?

Rolvedon patient assistance information can be found through ACCESS4ME at the URL: https://www.access4me.com/patient-support/ Visit Here →

Where can I find Rolvedon prescribing information?

ROLVEDON prescribing information can be found at the link below: Visit Here →

Where can I find Rolvedon side effect information?

Our team has not yet identified a source of side effects information for ROLVEDON. Please check back in a few weeks.

Does billing ROLVEDON require JZ/JW wastage modifiers?

CMS has identified ROLVEDON(J1449) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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