ERYTHROCIN LACTOBIONATE J Code: J1364

Drug & Product Overview

HCPCS Descriptor Injection, erythromycin lactobionate, per 500 mg

HCPCS Added Date January 1, 1995

Manufacturer Hospira

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About ERYTHROCIN LACTOBIONATE

Erythrocin Lactobionate is a medication aligned to the HCPCS J Code: J1364 for billing, pricing, and reimbursement purposes in the United States. Classified under Antibiotic, it is administered via the intravenous route and manufactured by Hospira.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00409-6476-44	Erythromycin Lactobionate	Pfizer Inc	10	500 MG
00409-6482-01	Erythrocin Lactobionate	Hospira, Inc.	10	500 MG / 10 ML
14789-0116-05	Erythromycin Lactobionate	Nexus Pharmaceuticals, LLC	5	500 MG

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ERYTHROCIN LACTOBIONATE Pricing & Reimbursement

J1364 Private Payer Reimbursement

$31.99 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

ERYTHROCIN LACTOBIONATE CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Erythrocin Lactobionate (J1364) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1364. Wastage billing guide →

ERYTHROCIN LACTOBIONATE Medically Unlikely Edits (MUE)

The most billing units of J1364 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

2 units / day

= 1,000 mg per day

Hospital Outpatient

8 units / day

= 4,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ERYTHROCIN LACTOBIONATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute pelvic inflammatory disease Group A beta-hemolytic streptococcal infections of the upper respiratory tract (prevention of initial attacks of rheumatic fever) Legionnaires' Disease Prevention of bacterial endocarditis Prevention of recurrent attacks of rheumatic fever Severe infections

Drug Class

Decreased Sebaceous Gland Activity [PE]Macrolide Antimicrobial [EPC]Macrolide [EPC]Macrolides [CS]

Frequently Asked Questions

Is there an available Erythrocin Lactobionate billing and coding guide?

We have not yet identified a manufacturer source of Erythrocin Lactobionate billing and coding information.

Are there any available Erythrocin Lactobionate patient assistance programs?

Our team did not identify a source for Erythrocin Lactobionate patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Erythrocin Lactobionate prescribing information?

Our team is still working to identify a prescribing information source for ERYTHROCIN LACTOBIONATE

Where can I find Erythrocin Lactobionate side effect information?

Our team has not yet identified a source of side effects information for ERYTHROCIN LACTOBIONATE. Please check back in a few weeks.

Does billing ERYTHROCIN LACTOBIONATE require JZ/JW wastage modifiers?

CMS does not include ERYTHROCIN LACTOBIONATE (J1364) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1364. For more information, visit the link below.

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