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Updated October 1st, 2026

BKEMV Q Code: Q5152

Injection, eculizumab-aeeb (bkemv), biosimilar, 2 mg

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Medicare Payment Limit ?
$40.412
/ HCPCS billing unit
APC Payment Limit ?
$40.412
/ HCPCS billing unit · APC 0846
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, eculizumab-aeeb (bkemv), biosimilar, 2 mg
HCPCS Added Date April 1, 2025
Manufacturer Amgen
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection, Solution, Concentrate

About BKEMV

Bkemv is a medication aligned to the HCPCS Q Code: Q5152 for billing, pricing, and reimbursement purposes in the United States. Classified under Immunology, it is administered via the intravenous route and manufactured by Amgen.

According to CMS Drug Use Information: This medication is used to treat a certain blood disorder (paroxysmal nocturnal hemoglobinuria). This disorder can cause a decrease in red blood cells (anemia). This medication helps to block the decrease in red blood cells and can improve the symptoms of anemia (such as tiredness, shortness of breath) and decrease the need for blood transfusions. This medication may also be used to treat a certain immune system disorder (atypical Hemolytic Uremic Syndrome). It helps to prevent blood clots caused by this disorder. Eculizumab is also used to treat a certain muscle condition (generalized Myasthenia Gravis). It may help to improve symptoms of this condition (such as difficulty swallowing, trouble breathing). Eculizumab is also used to treat a certain nervous system disorder that affects the spinal cord and eye nerve (neuromyelitis optica spectrum disorder). It may help to reduce the number of hospital stays due to the disease. This monograph is about the following eculizumab products: eculizumab, eculizumab-aagh, eculizumab-aeeb.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
55513-0180-01 Bkemv Amgen Inc 150 300 MG / 30 ML
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BKEMV Pricing & Reimbursement

Q5152 Private Payer Reimbursement
$42.24 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q4 2026

Eculizumab Biosimilar Information:

BKEMV Approval Date: May 28, 2024

Product Name HCPCS Code Active Ingredient BLA Type
Soliris J1299 Eculizumab 351(a) Originator Product
Bkemv Q5152 Eculizumab 351(k) Interchangeable
Epysqli Q5151 Eculizumab 351(k) Interchangeable

BKEMV CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

BKEMV Medically Unlikely Edits (MUE)

The most billing units of Q5152 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 2 mg.

Practitioner Office & Hospital Outpatient
600 units / day
= 1,200 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

BKEMV Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Atypical Hemolytic Uremic Syndrome (aHUS) Generalized Myasthenia Gravis (gMG) Neuromyelitis Optica Spectrum Disorder (NMOSD) Paroxysmal Nocturnal Hemoglobinuria (PNH)
Drug Class
Complement Inhibitor [EPC]Complement Inhibitors [MoA]

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Frequently Asked Questions

Is there a manufacturer-published billing and coding guide for Bkemv?
Billing and coding information for BKEMV can be found through AMGEN. Visit Here →
Are there any available patient assistance programs for Bkemv?
BKEMV patient assistance information can be found through AMGEN. Visit Here →
Where can I find Bkemv prescribing information?
Bkemv prescribing information can be found at the link below. Visit Here →
Is there available side effect information for Bkemv?
Side effect information for Bkemv can be found through Medline Plus at the link below. Visit Here →
Does billing BKEMV require JZ/JW wastage modifiers?
CMS does not include BKEMV (Q5152) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q5152. For more information, visit the link below.

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