BICILLIN C-R J Code: J0558

Drug & Product Overview

HCPCS Descriptor Injection, penicillin g benzathine and penicillin g procaine, 100,000 units

HCPCS Added Date January 1, 2011

Manufacturer Pfizer

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Form Injection, Suspension

About BICILLIN C-R

Bicillin C-R is a medication aligned to the HCPCS J Code: J0558 for billing, pricing, and reimbursement purposes in the United States. This Antibiotic medication is administered via the intramuscular route and manufactured by Pfizer.

According to CMS Drug Use Information: This medication is used to treat a wide variety of bacterial infections. This medication is known as a long-acting natural penicillin antibiotic. It works by stopping the growth of bacteria. This medication should not be used to treat sexually transmitted diseases (such as syphilis, gonorrhea).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
60793-0600-10	Bicillin Cr	Pfizer Laboratories Div Pfizer Inc	120	Bicillin Cr Intramuscu lar Injection 60… Login for More
60793-0601-10	Bicillin Cr	Pfizer Laboratories Div Pfizer Inc	120	Bicillin Cr Intramuscu lar Injection 60… Login for More
60793-0602-10	Bicillin C-R 900/300	Pfizer Laboratories Div Pfizer Inc	120	Bicillin C-R 900/300 I ntramuscular Inj… Login for More

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BICILLIN C-R Pricing & Reimbursement

J0558 Private Payer Reimbursement

$19.39 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

BICILLIN C-R CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

CMS does not include Bicillin C-R (J0558) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0558. Wastage billing guide →

BICILLIN C-R Medically Unlikely Edits (MUE)

The most billing units of J0558 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 100,000 units.

Practitioner Office & Hospital Outpatient

24 units / day

= 2,400 ,000 units per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

BICILLIN C-R Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Pneumococcal Infections (except pneumococcal meningitis) Pneumococcal infections (except pneumococcal meningitis) Streptococcal Infections Group A (upper-respiratory tract, skin and soft-tissue infections, scarlet fever, erysipelas) Streptococcal infections (upper-respiratory tract, skin and soft-tissue infections, scarlet fever, erysipelas)

Drug Class

Penicillin-class Antibacterial [EPC]Penicillins [CS]

Frequently Asked Questions

Is there an available Bicillin C-R billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for BICILLIN C-R.

Are there any available Bicillin C-R patient assistance programs?

BICILLIN C-R patient assistance information can be found through Pfizer. Visit Here →

Where can I find Bicillin C-R prescribing information?

BICILLIN C-R prescribing information can be found at the link below: Visit Here →

Where can I find Bicillin C-R side effect information?

Our team has not yet identified a source of side effects information for BICILLIN C-R. Please check back in a few weeks.

Does billing BICILLIN C-R require JZ/JW wastage modifiers?

CMS does not include BICILLIN C-R (J0558) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0558. For more information, visit the link below.

About BuyandBill.com:

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