urokinase J Code: J3365

HCPCS Code Discontinued J3365 was deactivated effective December 31, 2025 and is no longer valid for billing. Confirm the current replacement code before submitting claims.

Drug & Product Overview

HCPCS Descriptor Injection, iv, urokinase, 250,000 i.u. vial

HCPCS Added Date January 1, 1992

Route of Administration Intravenous

Generic Status HCPCS Discontinued

About UROKINASE

Urokinase is a medication aligned to the HCPCS J Code: J3365 for billing, pricing, and reimbursement purposes in the United States. Classified under Hematology, it is administered via the intravenous route.

Manufacturers, reach out to us to add more information.

NDC Code Information

No NDC packages are aligned to J3365 in publicly available CMS files.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
No public NDC alignments

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UROKINASE CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Urokinase (J3365) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3365. Wastage billing guide →

Frequently Asked Questions

Is there an available urokinase billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for urokinase. Please reach out to us if this is a mistake.

Are there any available urokinase patient assistance programs?

Our team has not identified a source of patient assistance information for urokinase. Please reach out to us if this is a mistake.

Where can I find urokinase prescribing information?

No available source of prescribing information for urokinase

Where can I find urokinase side effect information?

A link for urokinase side effect information is not available.

Does billing urokinase require JZ/JW wastage modifiers?

CMS does not include UROKINASE (J3365) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3365. For more information, visit the link below.

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