AMINOCAPROIC ACID J Code: J0281

Drug & Product Overview

HCPCS Descriptor Injection, aminocaproic acid, 1 gram

HCPCS Added Date April 1, 2025

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose, Multi-Dose

Dosage Form Injection, Solution

About AMINOCAPROIC ACID

Aminocaproic ACID is a medication aligned to the HCPCS J Code: J0281 for billing, pricing, and reimbursement purposes in the United States. Classified under Hematology, it is administered via the intravenous route and manufactured by multiple companies.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 4 of 7 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00409-4346-73	Aminocaproic Acid	Hospira, Inc.	125	Aminocaproic Acid Intr avenous Injectio… Login for More
00517-9120-25	Aminocaproic Acid	American Regent, Inc.	125	Aminocaproic Acid Intr avenous Injectio… Login for More
00517-9191-25	Aminocaproic Acid	American Regent, Inc.	125	Aminocaproic Acid Intr avenous Injectio… Login for More
72572-0015-25	Aminocaproic Acid	Civica, Inc.	125	Aminocaproic Acid Intr avenous Injectio… Login for More
•••••-••••-•• Log in to view	AMINOCAPROIC ACID
	AMINOCAPROIC ACID
	AMINOCAPROIC ACID

Login to view 3 more NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

AMINOCAPROIC ACID Pricing & Reimbursement

J0281 Private Payer Reimbursement

$1.47 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Aminocaproic Acid 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J0281	Generic Code (Multiple Manufacturers)	Aminocaproic Acid	Injection, aminocaproic acid, 1 gram

AMINOCAPROIC ACID CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

AMINOCAPROIC ACID Medically Unlikely Edits (MUE)

The most billing units of J0281 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 gm.

Practitioner Office & Hospital Outpatient

30 units / day

= 30 gm per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

AMINOCAPROIC ACID Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

acute bleeding syndromes due to elevated fibrinolytic activity

Drug Class

Antifibrinolytic Agent [EPC]Decreased Fibrinolysis [PE]

Frequently Asked Questions

Is there a manufacturer-published AMINOCAPROIC ACID billing and coding guide?

Our team has not identified a manufacturer-published billing and coding guide for AMINOCAPROIC ACID.

What are the available AMINOCAPROIC ACID patient assistance programs?

Our team has not identified a source of patient assitsance information for AMINOCAPROIC ACID.

Where can I find AMINOCAPROIC ACID prescribing information?

AMINOCAPROIC ACID prescribing information can be found at the link below. Visit Here →

Where can I find AMINOCAPROIC ACID side effect information?

Side effect information for AMINOCAPROIC ACID can be found at the following source.

Does billing AMINOCAPROIC ACID require JZ/JW wastage modifiers?

CMS does not include AMINOCAPROIC ACID (J0281) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0281. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.