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Updated July 1st, 2026

ANGIOMAX J Code: J0583

Injection, bivalirudin, 1 mg

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Q4 2026 Medicare Payment Limit for J0583, effective October 1, 2026: $0.165 per HCPCS billing unit, down 0.6% from $0.166. From CMS's final file.

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Medicare Payment Limit ?
$0.166
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
21
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Drug & Product Overview

HCPCS Descriptor Injection, bivalirudin, 1 mg
HCPCS Added Date January 1, 2004
Manufacturer Multiple Manufacturers
Route of Administration Intracavernous, Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection | Injection, Powder, Lyophilized, For Solution | Injection, Powder, Lyophilized, For Suspension | Not Available

About ANGIOMAX

Angiomax is a medication aligned to the HCPCS J Code: J0583 for billing, pricing, and reimbursement purposes in the United States. It is a Hematology drug administered via the intracavernous or intravenous routes and manufactured by multiple companies.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 21 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00781-3158-95 bivalirudin Sandoz Inc 2500 250 MG
00781-9158-95 Bivalirudin Sandoz Inc. 2500 250 MG
16729-0275-67 Bivalirudin Accord Healthcare, Inc. 2500 250 MG / 5 ML
55111-0652-37 Bivalirudin Dr. Reddy's Laboratories Limited 2500 250 MG
55150-0210-10 Bivalirudin Eugia Us Llc 2500 250 MG
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ANGIOMAX Pricing & Reimbursement

J0583 Private Payer Reimbursement
$0.45 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Bivalirudin 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J0582 Par Pharmaceutical, Inc Bivalirudin Injection, bivalirudin (endo), not therapeutically equivalent to j0583, 1 mg
J0583 Generic Code (Multiple Manufacturers) Bivalirudin Injection, bivalirudin, 1 mg

ANGIOMAX CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Angiomax (J0583) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ANGIOMAX Medically Unlikely Edits (MUE)

The most billing units of J0583 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
250 units / day
= 250 mg per day
Hospital Outpatient
1,250 units / day
= 1,250 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

ANGIOMAX Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Percutaneous Coronary Intervention (PCI) Percutaneous Coronary Intervention (PCI) with STEMI Percutaneous Coronary Intervention (PCI) — STEMI
Drug Class
Anti-coagulant [EPC]Direct Thrombin Inhibitor [EPC]Thrombin Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Angiomax billing and coding guide?
We have not yet identified a manufacturer source of Angiomax billing and coding information.
Are there any available Angiomax patient assistance programs?
Our team did not identify a source for Angiomax patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Angiomax prescribing information?
ANGIOMAX prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Angiomax side effect information?
Our team has not yet identified a source of side effects information for ANGIOMAX. Please check back in a few weeks.
Does billing ANGIOMAX require JZ/JW wastage modifiers?
CMS has identified ANGIOMAX(J0583) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to ANGIOMAX.

J0582BIVALIRUDINInjection, bivalirudin (endo), not therapeutically equivalent to j0583, 1 mgPar Pharmaceutical, IncAdded October 1, 2025J1327EPTIFIBATIDEInjection, eptifibatide, 5 mgMultiple ManufacturersAdded January 1, 2000J0883ARGATROBANInjection, argatroban, 1 mg (for non-esrd use)Multiple ManufacturersAdded January 1, 2017J0884ARGATROBANInjection, argatroban, 1 mg (for esrd on dialysis)Multiple ManufacturersAdded January 1, 2017J0891ARGATROBANInjection, argatroban (accord), not therapeutically equivalent to j0883, 1 mg (for non-esrd use)AccordAdded January 1, 2023J0892ARGATROBANInjection, argatroban (accord), not therapeutically equivalent to j0884, 1 mg (for esrd on dialysis)AccordAdded January 1, 2023J0898ArgatrobanInjection, argatroban (auromedics), not therapeutically equivalent to j0883, 1 mg (for non-esrd use)Eugia USAdded January 1, 2023J0899ArgatrobanInjection, argatroban (auromedics), not therapeutically equivalent to j0884, 1 mg (for esrd on dialysis)Eugia USAdded January 1, 2023C9047CABLIVIInjection, caplacizumab-yhdp, 1 mgGenzymeAdded July 1, 2019C9094ENJAYMOInj, sutimlimab-jome, 10 mgBioverativAdded July 1, 2022