TRETTEN J Code: J7181

Drug & Product Overview

HCPCS Descriptor Injection, factor xiii a-subunit, (recombinant), per iu

HCPCS Added Date January 1, 2015

Manufacturer Novo Nordisk

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit

About TRETTEN

Tretten is a medication aligned to the HCPCS J Code: J7181 for billing, pricing, and reimbursement purposes in the United States. Classified under Hematology, it is administered via the intravenous route and manufactured by Novo Nordisk.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00169-7013-01	Tretten	Novo Nordisk	1	Kit

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TRETTEN Pricing & Reimbursement

J7181 Private Payer Reimbursement

$18.42 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

TRETTEN CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Tretten (J7181) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

TRETTEN Medically Unlikely Edits (MUE)

The most billing units of J7181 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 iu.

Practitioner Office & Hospital Outpatient

3,850 units / day

= 3,850 iu per day

MAI 1 · Line Edit. Per-line limit: units are checked per claim line; medically necessary units beyond the limit may be billable on separate lines with appropriate modifiers. See all MUE limits →

TRETTEN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Congenital Factor XIII A-subunit deficiency

Frequently Asked Questions

Is there an available Tretten billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for TRETTEN.

Are there any available Tretten patient assistance programs?

TRETTEN patient assistance information can be found through Novo Nordisk. Visit Here →

Where can I find Tretten prescribing information?

TRETTEN prescribing information can be found at the link below: Visit Here →

Where can I find Tretten side effect information?

Our team has not yet identified a source of side effects information for TRETTEN. Please check back in a few weeks.

Does billing TRETTEN require JZ/JW wastage modifiers?

CMS has identified TRETTEN(J7181) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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