SynoJoynt J Code: J7331

Drug & Product Overview

HCPCS Descriptor Hyaluronan or derivative, synojoynt, for intra-articular injection, 1 mg

HCPCS Added Date October 1, 2019

Manufacturer Arthrex

Route of Administration Intra-Articular

Generic Status Single-Source; Branded

About SynoJoynt

SynoJoynt is a medication aligned to the HCPCS J Code: J7331 for billing, pricing, and reimbursement purposes in the United States. Classified under Orthopedic, it is administered via the intra-articular route and manufactured by Arthrex.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

1 NDC package is crosswalked to J7331. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	SynoJoynt

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SynoJoynt Pricing & Reimbursement

J7331 Private Payer Reimbursement

$3.27 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

SynoJoynt CPT Administration Codes

CPT Code	Description
20610	Arthrocentesis, aspiration and/or injection, major joint or bursa (eg, shoulder, hip, knee, subacromial bursa); without ultrasound guidance
20611	Arthrocentesis, aspiration and/or injection into a joint or bursa (eg, subacromial bursa), under ultrasound guidance with permanent recording and reporting.

Not on the CMS JW / JZ list

CMS does not include SynoJoynt (J7331) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7331. Wastage billing guide →

SynoJoynt Medically Unlikely Edits (MUE)

The most billing units of J7331 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

40 units / day

= 40 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

SynoJoynt Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Osteoarthritis of the knee

Frequently Asked Questions

Is there an available Synojoynt billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for SynoJoynt.

Are there any available Synojoynt patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for SynoJoynt.

Where can I find Synojoynt prescribing information?

SynoJoynt prescribing information can be found at the link below: Visit Here →

Where can I find Synojoynt side effect information?

Our team has not yet identified a source of side effects information for SynoJoynt. Please check back in a few weeks.

Does billing SynoJoynt require JZ/JW wastage modifiers?

CMS does not include SynoJoynt (J7331) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7331. For more information, visit the link below.

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