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Updated July 1st, 2026

Euflexxa J Code: J7323

Hyaluronan or derivative, euflexxa, for intra-articular injection, per dose

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Q4 2026 Medicare Payment Limit for J7323, effective October 1, 2026: $103.603 per HCPCS billing unit, up 5.6% from $98.137. From CMS's final file.

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Medicare Payment Limit ?
$98.137
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$98.137
/ HCPCS billing unit · APC 0875
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Hyaluronan or derivative, euflexxa, for intra-articular injection, per dose
HCPCS Added Date January 1, 2008
Manufacturer Ferring Pharmaceuticals
Route of Administration Intra-Articular
Generic Status Single-Source; Branded

About Euflexxa

Euflexxa is a medication aligned to the HCPCS J Code: J7323 for billing, pricing, and reimbursement purposes in the United States. This Orthopedic medication is administered via the intra-articular route and manufactured by Ferring Pharmaceuticals.

According to CMS Drug Use Information: This medication is used to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy. Hyaluronate (also known as hyaluronan) is similar to a substance that occurs naturally in the joints. It may work by acting as a lubricant and shock absorber in the joint, helping the knee to move smoothly, thereby lessening pain.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
55566-4100-01 Euflexxa Ferring Pharmaceuticals Inc. 3 20 MG / 2 ML
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Euflexxa Pricing & Reimbursement

J7323 Private Payer Reimbursement
$109.59 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Euflexxa CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
20610 Arthrocentesis, aspiration and/or injection, major joint or bursa (eg, shoulder, hip, knee, subacromial bursa); without ultrasound guidance
20611 Arthrocentesis, aspiration and/or injection into a joint or bursa (eg, subacromial bursa), under ultrasound guidance with permanent recording and reporting.
Not on the CMS JW / JZ list

CMS does not include Euflexxa (J7323) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7323. Wastage billing guide →

Euflexxa Medically Unlikely Edits (MUE)

The most billing units of J7323 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 dose.

Practitioner Office & Hospital Outpatient
2 units / day
Same limit in both settings

MAI 2 · Date of Service Edit: Policy. Absolute per-day limit set by policy or regulation; units above it are not payable, and denials are not appealable on medical-necessity grounds. See all MUE limits →

Euflexxa Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Osteoarthritis of the knee

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Frequently Asked Questions

Is there an available Euflexxa billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for Euflexxa.
Are there any available Euflexxa patient assistance programs?
Euflexxa patient assistance information can be found through Ferring Pharmaceuticals. Visit Here →
Where can I find Euflexxa prescribing information?
Euflexxa prescribing information can be found at the link below: Visit Here →
Where can I find Euflexxa side effect information?
Our team has not yet identified a source of side effects information for Euflexxa. Please check back in a few weeks.
Does billing Euflexxa require JZ/JW wastage modifiers?
CMS does not include Euflexxa (J7323) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7323. For more information, visit the link below.

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