Home Drug Codes J Codes J1300 · SOLIRIS
Updated July 1st, 2026

SOLIRIS J Code: J1300

Injection, eculizumab, 10 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, eculizumab, 10 mg
HCPCS Added Date January 1, 2008
Manufacturer Alexion Pharmaceuticals
Route of Administration Intravenous
Generic Status HCPCS Discontinued
Dosage Type Single-Dose
Dosage Form Injection, Solution, Concentrate

About SOLIRIS

Soliris is a medication aligned to the HCPCS J Code: J1300 for billing, pricing, and reimbursement purposes in the United States. It is an Immunology drug administered via the intravenous route and manufactured by Alexion Pharmaceuticals.

According to CMS Drug Use Information: This medication is used to treat a certain blood disorder (paroxysmal nocturnal hemoglobinuria). This disorder can cause a decrease in red blood cells (anemia). This medication helps to block the decrease in red blood cells and can improve the symptoms of anemia (such as tiredness, shortness of breath) and decrease the need for blood transfusions. This medication may also be used to treat a certain immune system disorder (atypical Hemolytic Uremic Syndrome). It helps to prevent blood clots caused by this disorder. Eculizumab is also used to treat a certain muscle condition (generalized Myasthenia Gravis). It may help to improve symptoms of this condition (such as difficulty swallowing, trouble breathing). Eculizumab is also used to treat a certain nervous system disorder that affects the spinal cord and eye nerve (neuromyelitis optica spectrum disorder). It may help to reduce the number of hospital stays due to the disease. This monograph is about the following eculizumab products: eculizumab, eculizumab-aagh, eculizumab-aeeb.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

1 NDC package is crosswalked to J1300. Package detail is available to logged-in subscribers.

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Biosimilar Information

SOLIRIS Approval Date: March 16, 2007

Product Name HCPCS Code Active Ingredient BLA Type
EPYSQLI Q5151 Eculizumab 351(K) Biosimilar
BKEMV Q5152 Eculizumab 351(K) Interchangeable
SOLIRIS J1299 Eculizumab 351(a) Originator Product

SOLIRIS CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Soliris (J1300) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

SOLIRIS Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Atypical Hemolytic Uremic Syndrome (aHUS) Generalized Myasthenia Gravis (gMG) Neuromyelitis Optica Spectrum Disorder (NMOSD) Paroxysmal Nocturnal Hemoglobinuria (PNH)
Drug Class
Complement Inhibitor [EPC]Complement Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Soliris billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for SOLIRIS.
Are there any available Soliris patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for SOLIRIS.
Where can I find Soliris prescribing information?
SOLIRIS prescribing information can be found at the link below: Visit Here →
Where can I find Soliris side effect information?
Information regarding SOLIRIS's side effects can be found at MedlinePlus Visit Here →
Does billing SOLIRIS require JZ/JW wastage modifiers?
CMS has identified SOLIRIS(J1300) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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