Home › Drug Codes › J Codes › J2791 · RHOPHYLAC
Updated July 1st, 2026

RHOPHYLAC J Code: J2791

Injection, rho(d) immune globulin (human), (rhophylac), intramuscular or intravenous, 100 iu

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Q4 2026 Medicare Payment Limit for J2791, effective October 1, 2026: $4.837 per HCPCS billing unit, down 0.8% from $4.878. From CMS's final file.

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Medicare Payment Limit ?
$4.878
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, rho(d) immune globulin (human), (rhophylac), intramuscular or intravenous, 100 iu
HCPCS Added Date January 1, 2008
Manufacturer CSL Behring
Route of Administration Intramuscular, Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Solution

About RHOPHYLAC

Rhophylac is a medication aligned to the HCPCS J Code: J2791 for billing, pricing, and reimbursement purposes in the United States. It is an Immunology drug administered via the intramuscular or intravenous routes and manufactured by CSL Behring.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
44206-0300-01 Rhophylac CSL Behring AG 15 Rhophylac Intramuscula r Solution 1500 … Login for More
44206-0300-10 Rhophylac CSL Behring AG 150 Rhophylac Intramuscula r Solution 1500 … Login for More
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RHOPHYLAC Pricing & Reimbursement

J2791 Private Payer Reimbursement
$4.69 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

RHOPHYLAC CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96372 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular Login for More
Not on the CMS JW / JZ list

CMS does not include Rhophylac (J2791) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2791. Wastage billing guide →

RHOPHYLAC Medically Unlikely Edits (MUE)

The most billing units of J2791 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 100 iu.

Practitioner Office & Hospital Outpatient
15 units / day
= 1,500 iu per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

iu Enter a dose to see how many billing units it is and whether it is under the limit.

RHOPHYLAC Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Immune Thrombocytopenic Purpura (ITP) Suppression of Rh Isoimmunization
Drug Class
Endogenous Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

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Frequently Asked Questions

Is there an available Rhophylac billing and coding guide?
Billing and coding information for RHOPHYLAC can be found through CSL Behring. Visit Here →
Are there any available Rhophylac patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for RHOPHYLAC.
Where can I find Rhophylac prescribing information?
RHOPHYLAC prescribing information can be found at the link below: Visit Here →
Where can I find Rhophylac side effect information?
Our team has not yet identified a source of side effects information for RHOPHYLAC. Please check back in a few weeks.
Does billing RHOPHYLAC require JZ/JW wastage modifiers?
CMS does not include RHOPHYLAC (J2791) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2791. For more information, visit the link below.

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