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Updated July 1st, 2026

HYPERRHO S-D J Code: J2790

Injection, rho d immune globulin, human, full dose, 300 micrograms (1500 i.u.)

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Q4 2026 Medicare Payment Limit for J2790, effective October 1, 2026: $82.081 per HCPCS billing unit, down 3.6% from $85.125. From CMS's final file.

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Medicare Payment Limit ?
$85.125
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
6
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Drug & Product Overview

HCPCS Descriptor Injection, rho d immune globulin, human, full dose, 300 micrograms (1500 i.u.)
HCPCS Added Date January 1, 1986
Manufacturer Multiple Manufacturers
Route of Administration Intramuscular
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection, Solution | Solution

About HYPERRHO S-D

Hyperrho S-D is a medication aligned to the HCPCS J Code: J2790 for billing, pricing, and reimbursement purposes in the United States. This Immunology medication is administered via the intramuscular route and manufactured by multiple companies.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 6 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00562-7805-01 RhoGAM Ultra-Filtered PLUS Kedrion Biopharma Inc 1 300 UG
00562-7805-05 RhoGAM Ultra-Filtered PLUS Kedrion Biopharma Inc 5 300 UG
00562-7805-25 RhoGAM Ultra-Filtered PLUS Kedrion Biopharma Inc 25 300 UG
13533-0631-02 Hyperrho Full Dose GRIFOLS USA, LLC 1 Hyperrho Full Dose Int ramuscular Solut… Login for More
13533-0631-11 Hyperrho Full Dose GRIFOLS USA, LLC 10 Hyperrho Full Dose Int ramuscular Solut… Login for More
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HYPERRHO S-D Pricing & Reimbursement

J2790 Private Payer Reimbursement
$81.82 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

HYPERRHO S-D CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
Not on the CMS JW / JZ list

CMS does not include Hyperrho S-D (J2790) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2790. Wastage billing guide →

HYPERRHO S-D Medically Unlikely Edits (MUE)

The most billing units of J2790 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 300 mcg (1500 iu). The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
1 unit / day
= 300 mcg (1500 iu) per day
Hospital Outpatient
3 units / day
= 900 mcg (1500 iu) per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mcg (1500 iu) Enter a dose to see how many billing units it is and whether it is under the limit.

HYPERRHO S-D Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Pregnancy and other obstetrical conditions Prevention of Rh isoimmunization following incompatible transfusion Rh hemolytic disease of the newborn prevention Transfusion of Rh-incompatible blood or blood products
Drug Class
Endogenous Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

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Frequently Asked Questions

Is there an available Hyperrho S-D billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for HYPERRHO S-D.
Are there any available Hyperrho S-D patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for HYPERRHO S-D.
Where can I find Hyperrho S-D prescribing information?
Our team is still working to identify a prescribing information source for HYPERRHO S-D
Where can I find Hyperrho S-D side effect information?
Our team has not yet identified a source of side effects information for HYPERRHO S-D. Please check back in a few weeks.
Does billing HYPERRHO S-D require JZ/JW wastage modifiers?
CMS does not include HYPERRHO S-D (J2790) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2790. For more information, visit the link below.

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