HYPERRHO S-D J Code: J2788

Drug & Product Overview

HCPCS Descriptor Injection, rho d immune globulin, human, minidose, 50 micrograms (250 i.u.)

HCPCS Added Date January 1, 2003

Manufacturer Grifols

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Form Solution

About HYPERRHO S-D

Hyperrho S-D is a medication aligned to the HCPCS J Code: J2788 for billing, pricing, and reimbursement purposes in the United States. It is a Hematology drug administered via the intramuscular route and manufactured by Grifols.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. Showing 1 of 2 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
13533-0661-06	Hyperrho Mini-Dose	GRIFOLS USA, LLC	10	Hyperrho Mini-Dose Int ramuscular Solut… Login for More
•••••-••••-•• Log in to view	HYPERRHO S-D

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HYPERRHO S-D Pricing & Reimbursement

J2788 Private Payer Reimbursement

$23.78 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

HYPERRHO S-D CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

CMS does not include Hyperrho S-D (J2788) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2788. Wastage billing guide →

HYPERRHO S-D Medically Unlikely Edits (MUE)

The most billing units of J2788 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 50 mcg.

Practitioner Office & Hospital Outpatient

1 unit / day

= 50 mcg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

HYPERRHO S-D Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Rh isoimmunization prevention following spontaneous or induced abortion

Drug Class

Endogenous Antigen Neutralization [MoA]Human Immunoglobulin G [EPC]Immunoglobulins [CS]Passively Acquired Immunity [PE]

Frequently Asked Questions

Is there an available Hyperrho S-D billing and coding guide?

Billing and coding information for HYPERRHO S-D can be found through Grifols. Visit Here →

Are there any available Hyperrho S-D patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for HYPERRHO S-D.

Where can I find Hyperrho S-D prescribing information?

Our team is still working to identify a prescribing information source for HYPERRHO S-D

Where can I find Hyperrho S-D side effect information?

Our team has not yet identified a source of side effects information for HYPERRHO S-D. Please check back in a few weeks.

Does billing HYPERRHO S-D require JZ/JW wastage modifiers?

CMS does not include HYPERRHO S-D (J2788) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2788. For more information, visit the link below.

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