PROGRAF J Code: J7507

Drug & Product Overview

HCPCS Descriptor Tacrolimus, immediate release, oral, 1 mg

HCPCS Added Date January 1, 1995

Manufacturer Multiple Manufacturers

Route of Administration Oral

Generic Status Multi-Source; Generic

Dosage Form Capsule | Capsule, Gelatin Coated | Not Available

About PROGRAF

Prograf is a medication aligned to the HCPCS J Code: J7507 for billing, pricing, and reimbursement purposes in the United States. It is an Immunosuppressant drug administered via the oral route and manufactured by multiple companies.

According to CMS Drug Use Information: Tacrolimus is used with other medications to prevent rejection of a kidney, heart, liver, or lung transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 47 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00378-2045-01	Tacrolimus	Mylan Pharmaceuticals Inc.	50	0.5 MG
00469-0607-73	Prograf	Astellas Pharma US, Inc.	50	0.5 MG
00781-2102-01	Tacrolimus	Sandoz Inc.	50	0.5 MG
00904-7097-61	Tacrolimus	Major Pharmaceuticals	100	1 MG
16714-0098-01	tacrolimus	NORTHSTAR RX LLC	50	0.5 MG
•••••-••••-•• Log in to view	PROGRAF
	PROGRAF
	PROGRAF

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PROGRAF Pricing & Reimbursement

J7507 Private Payer Reimbursement

$0.42 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

PROGRAF Medically Unlikely Edits (MUE)

The most billing units of J7507 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

0 units / day

Not payable in this setting

Hospital Outpatient

40 units / day

= 40 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Not on the CMS JW / JZ list

CMS does not include Prograf (J7507) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7507. Wastage billing guide →

PROGRAF Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Heart Transplant Kidney Transplant Liver Transplant Lung Transplant Organ Rejection in Heart Transplant Organ Rejection in Kidney Transplant Organ Rejection in Liver Transplant Prophylaxis of Organ Rejection in Heart Transplant Prophylaxis of Organ Rejection in Kidney Transplant Prophylaxis of Organ Rejection in Liver Transplant Prophylaxis of organ rejection in heart transplant Prophylaxis of organ rejection in kidney or liver transplant Prophylaxis of organ rejection in kidney transplant Prophylaxis of organ rejection in liver transplant

Drug Class

Calcineurin Inhibitor Immunosuppressant [EPC]Calcineurin Inhibitors [MoA]

Frequently Asked Questions

Is there an available Prograf billing and coding guide?

We have not yet identified a manufacturer source of Prograf billing and coding information.

Are there any available Prograf patient assistance programs?

Our team did not identify a source for Prograf patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Prograf prescribing information?

PROGRAF prescribing information can be found at the link below: Visit Here →

Where can I find Prograf side effect information?

Information regarding PROGRAF's side effects can be found at MedlinePlus Visit Here →

Does billing PROGRAF require JZ/JW wastage modifiers?

CMS does not include PROGRAF (J7507) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7507. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.