Home › Drug Codes › J Codes › J7507 · PROGRAF
Updated July 1st, 2026

PROGRAF J Code: J7507

Tacrolimus, immediate release, oral, 1 mg

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Q4 2026 Medicare Payment Limit for J7507, effective October 1, 2026: $0.162 per HCPCS billing unit, down 19.0% from $0.20. From CMS's final file.

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Medicare Payment Limit ?
$0.20
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
47
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Drug & Product Overview

HCPCS Descriptor Tacrolimus, immediate release, oral, 1 mg
HCPCS Added Date January 1, 1995
Manufacturer Multiple Manufacturers
Route of Administration Oral
Generic Status Multi-Source; Generic
Dosage Form Capsule | Capsule, Gelatin Coated | Not Available

About PROGRAF

Prograf is a medication aligned to the HCPCS J Code: J7507 for billing, pricing, and reimbursement purposes in the United States. It is an Immunosuppressant drug administered via the oral route and manufactured by multiple companies.

According to CMS Drug Use Information: Tacrolimus is used with other medications to prevent rejection of a kidney, heart, liver, or lung transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 47 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00378-2045-01 Tacrolimus Mylan Pharmaceuticals Inc. 50 .5 MG
00469-0607-73 Prograf Astellas Pharma US, Inc. 50 .5 MG
00781-2102-01 Tacrolimus Sandoz Inc. 50 .5 MG
00904-7097-61 Tacrolimus Major Pharmaceuticals 100 1 MG
16714-0098-01 tacrolimus NORTHSTAR RX LLC 50 .5 MG
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PROGRAF Pricing & Reimbursement

J7507 Private Payer Reimbursement
$0.42 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

PROGRAF Medically Unlikely Edits (MUE)

The most billing units of J7507 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
0 units / day
Not payable in this setting
Hospital Outpatient
40 units / day
= 40 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.
Not on the CMS JW / JZ list

CMS does not include Prograf (J7507) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7507. Wastage billing guide →

PROGRAF Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Heart Transplant Kidney Transplant Liver Transplant Lung Transplant Organ Rejection in Heart Transplant Organ Rejection in Kidney Transplant Organ Rejection in Liver Transplant Prophylaxis of Organ Rejection in Heart Transplant Prophylaxis of Organ Rejection in Kidney Transplant Prophylaxis of Organ Rejection in Liver Transplant Prophylaxis of organ rejection in heart transplant Prophylaxis of organ rejection in kidney transplant Prophylaxis of organ rejection in liver transplant
Drug Class
Calcineurin Inhibitor Immunosuppressant [EPC]Calcineurin Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Prograf billing and coding guide?
We have not yet identified a manufacturer source of Prograf billing and coding information.
Are there any available Prograf patient assistance programs?
Our team did not identify a source for Prograf patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Prograf prescribing information?
PROGRAF prescribing information can be found at the link below: Visit Here →
Where can I find Prograf side effect information?
Information regarding PROGRAF's side effects can be found at MedlinePlus Visit Here →
Does billing PROGRAF require JZ/JW wastage modifiers?
CMS does not include PROGRAF (J7507) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7507. For more information, visit the link below.

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