Home › Drug Codes › J Codes › J7503 · ENVARSUS XR
Updated July 1st, 2026

ENVARSUS XR J Code: J7503

Tacrolimus, extended release, (envarsus xr), oral, 0.25 mg

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Q4 2026 Medicare Payment Limit for J7503, effective October 1, 2026: $1.863 per HCPCS billing unit, unchanged from Q3 2026. From CMS's final file.

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Medicare Payment Limit ?
$1.863
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
6
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Drug & Product Overview

HCPCS Descriptor Tacrolimus, extended release, (envarsus xr), oral, 0.25 mg
HCPCS Added Date January 1, 2016
Manufacturer Veloxis Pharmaceuticals
Route of Administration Oral
Generic Status Single-Source; Branded
Dosage Form Tablet, Extended Release

About ENVARSUS XR

Envarsus XR is a medication aligned to the HCPCS J Code: J7503 for billing, pricing, and reimbursement purposes in the United States. This Immunosuppressant medication is administered via the oral route and manufactured by Veloxis Pharmaceuticals.

According to CMS Drug Use Information: Tacrolimus is used with other medications to prevent rejection of a kidney transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 6 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
68992-3010-01 Envarsus XR Veloxis Pharmaceuticals, Inc 400 1 MG
68992-3010-03 Envarsus XR Veloxis Pharmaceuticals, Inc 120 1 MG
68992-3040-01 Envarsus XR Veloxis Pharmaceuticals, Inc 1600 4 MG
68992-3040-03 Envarsus XR Veloxis Pharmaceuticals, Inc 480 4 MG
68992-3075-01 Envarsus XR Veloxis Pharmaceuticals, Inc 300 .75 MG
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ENVARSUS XR Pricing & Reimbursement

J7503 Private Payer Reimbursement
$1.65 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

ENVARSUS XR Medically Unlikely Edits (MUE)

The most billing units of J7503 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.25 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
0 units / day
Not payable in this setting
Hospital Outpatient
120 units / day
= 30 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.
Not on the CMS JW / JZ list

CMS does not include Envarsus XR (J7503) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7503. Wastage billing guide →

ENVARSUS XR Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Prophylaxis of Organ Rejection in Kidney Transplant
Drug Class
Calcineurin Inhibitor Immunosuppressant [EPC]Calcineurin Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Envarsus Xr billing and coding guide?
Billing and coding information for ENVARSUS XR can be found through Veloxis. Visit Here →
Are there any available Envarsus Xr patient assistance programs?
ENVARSUS XR patient assistance information can be found through Veloxis. Visit Here →
Where can I find Envarsus Xr prescribing information?
ENVARSUS XR prescribing information can be found at the link below: Visit Here →
Where can I find Envarsus Xr side effect information?
Information regarding ENVARSUS XR's side effects can be found at MedlinePlus Visit Here →
Does billing ENVARSUS XR require JZ/JW wastage modifiers?
CMS does not include ENVARSUS XR (J7503) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7503. For more information, visit the link below.

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