PROFILNINE J Code: J7194

Drug & Product Overview

HCPCS Descriptor Factor ix, complex, per i.u.

HCPCS Added Date January 1, 1986

Manufacturer Grifols

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit

About PROFILNINE

Profilnine is a medication aligned to the HCPCS J Code: J7194 for billing, pricing, and reimbursement purposes in the United States. This Hematology medication is administered via the intravenous route and manufactured by Grifols.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
68516-3210-01	Profilnine	GRIFOLS USA, LLC	1	Kit
68516-3211-02	Profilnine	GRIFOLS USA, LLC	1	Kit
68516-3212-02	Profilnine	GRIFOLS USA, LLC	1	Kit

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PROFILNINE Pricing & Reimbursement

J7194 Private Payer Reimbursement

$1.53 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

PROFILNINE CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Profilnine (J7194) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

PROFILNINE Medically Unlikely Edits (MUE)

The most billing units of J7194 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 iu.

Practitioner Office & Hospital Outpatient

9,000 units / day

= 9,000 iu per day

MAI 1 · Line Edit. Per-line limit: units are checked per claim line; medically necessary units beyond the limit may be billable on separate lines with appropriate modifiers. See all MUE limits →

PROFILNINE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Factor IX deficiency (hemophilia B)

Frequently Asked Questions

Is there an available Profilnine billing and coding guide?

We have not yet identified a manufacturer source of Profilnine billing and coding information.

Are there any available Profilnine patient assistance programs?

Our team did not identify a source for Profilnine patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Profilnine prescribing information?

PROFILNINE prescribing information can be found at the link below: Visit Here →

Where can I find Profilnine side effect information?

Our team has not yet identified a source of side effects information for PROFILNINE. Please check back in a few weeks.

Does billing PROFILNINE require JZ/JW wastage modifiers?

CMS has identified PROFILNINE(J7194) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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