Osvyrti PFS Q Code: Q5166
Injection, denosumab-desu (osvyrti/jubereq), biosimilar, 1 mg
Drug & Product Overview
About Osvyrti PFS
Osvyrti PFS is a medication aligned to the HCPCS Q Code: Q5166 for billing, pricing, and reimbursement purposes in the United States. It is an Osteoporosis drug administered via the subcutaneous route and manufactured by Accord.
Manufacturers, reach out to us to add more information.
NDC Code Information
Based on publicly available CMS files. The list of NDCs below is not exhaustive.
| NDC Code | Package | Manufacturer | HCPCS Units | WAC | AWP |
|---|---|---|---|---|---|
| 69448-0021-63 | 60 MG / 1 MLOsvyrti Subcutaneous Injection 60 MG/1ML - 1 SYRINGE in 1 CARTON (69448-021-63) / 1 mL in 1 SYRINGE | Accord BioPharma Inc. | 60 | $1,800.41 $30.007 / unit | $2,160.49 $36.008 / unit |
| 69448-0022-63 | 119 MG / 1.7 MLJubereq Subcutaneous Injection 119 MG/1.7ML - 1 VIAL, SINGLE-USE in 1 CARTON (69448-022-63) / 1.7 mL in 1 VIAL, SINGLE-USE | ACCORD BIOPHARMA INC. | 120 | $3,311.75 $27.598 / unit | $3,974.10 $33.118 / unit |
Effective 7/1/26 (WAC & AWP)
Osvyrti PFS Pricing & Reimbursement
Historical Graphing and Billing Calculator
Estimates only. Payer reimbursement varies by contract, site of care, and sequestration.
Denosumab Biosimilar Information:
Osvyrti PFS Approval Date: October 29, 2025
| Product Name | HCPCS Code | Active Ingredient | BLA Type |
|---|---|---|---|
| Prolia | J0897 | Denosumab | 351(a) Originator Product |
| Jubbonti and Wyost | Q5136 | Denosumab | 351(k) Interchangeable |
| Ospomyv and Xbryk | Q5159 | Denosumab | 351(k) Interchangeable |
| Stoboclo and Osenvelt | Q5157 | Denosumab | 351(k) Interchangeable |
| Bomyntra and Conexxence | Q5158 | Denosumab | 351(k) Interchangeable |
| Bildyos and Bilprevda | Q5162 | Denosumab | 351(k) Interchangeable |
| Aukelso and Bosaya | Q5161 | Denosumab | 351(k) Interchangeable |
| Enoby and Xtrenbo | Q5167 | Denosumab | 351(k) Interchangeable |
| Osvyrti and Jubereq | Q5166 | Denosumab | 351(k) Interchangeable |
| Oziltus | Q5165 | Denosumab | 351(k) Interchangeable |
| Boncresa | Q5171 | Denosumab | 351(k) Interchangeable |
| Ponlimsi | Q5173 | Denosumab | 351(k) Interchangeable |
Osvyrti PFS CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular |
This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →
Osvyrti PFS Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
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