Updated July 1st, 2026
PREDNISOLONE J Code: J7510
Prednisolone oral, per 5 mg
Q4 2026 Medicare Payment Limit for J7510, effective October 1, 2026: $0.498 per HCPCS billing unit, down 35.9% from $0.777. From CMS's final file.
Q4 2026 Final ?
$0.498 35.9%
Medicare Payment Limit ?
$0.777
/ HCPCS billing unit · Q3 2026 APC Payment Limit ?
Not published
CMS publishes none for Q3 2026 Drug & Product Overview
HCPCS Descriptor Prednisolone oral, per 5 mg
HCPCS Added Date January 1, 1996
Manufacturer Multiple Manufacturers
Route of Administration Oral
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Not Available | Solution | Syrup | Tablet | Tablet, Orally Disintegrating
About PREDNISOLONE
Prednisolone is a medication aligned to the HCPCS J Code: J7510 for billing, pricing, and reimbursement purposes in the United States. It is an Immunosuppressant drug administered via the oral route and manufactured by multiple companies.
According to CMS Drug Use Information: Prednisolone is a man-made form of a natural substance (corticosteroid hormone) made by the adrenal gland. It is used to treat conditions such as arthritis, blood problems, immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 5 of 38 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 00527-5406-68 | PrednisoLONE | Lannett Company, Inc. | 144 | 15 MG / 5 ML |
| 13925-0166-04 | Prednisolone Sodium Phosphate | Seton Pharmaceuticals, LLC | 24 | 5 MG / 5 ML |
| 23155-0927-51 | Prednisolone | Heritage Pharma Labs Inc. d/b/a Avet Pharmaceuticals Labs Inc. | 144 | 15 MG / 5 ML |
| 42658-0160-05 | Prednisolone | Hisun Pharmaceuticals USA, Inc. | 100 | 5 MG |
| 50090-0655-00 | Prednisolone | A-S Medication Solutions | 144 | Not Available |
| •••••-••••-•• Log in to view | PREDNISOLONE | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | PREDNISOLONE | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
| •••••-••••-•• Log in to view | PREDNISOLONE | •••••••••••• Log in to view | •••• Log in to view | ••• •• / • •• Log in to view |
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Login → PREDNISOLONE Pricing & Reimbursement
J7510 Private Payer Reimbursement
$0.95 / HCPCS unit as of Jan 2026
National median reimbursement across major commercial payers.
Create an account on PayerPrice for more information →
Historical Graphing and Billing Calculator
Estimated reimbursement ASP × 144 units × 1 dose
— / administration
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Login to use the calculator →PREDNISOLONE Medically Unlikely Edits (MUE)
The most billing units of J7510 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 5 mg. The limit is different in the office and the hospital. Use the one for your setting.
Practitioner Office
0 units / day
Not payable in this setting
Hospital Outpatient
60 units / day
= 300 mg per day
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
Not on the CMS JW / JZ list
CMS does not include Prednisolone (J7510) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7510. Wastage billing guide →
PREDNISOLONE Clinical Information
Indications and drug classification.
Treated Diseases & Conditions
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
Acquired (autoimmune) hemolytic anemia Acute Exacerbations of Multiple Sclerosis Acute Leukemia and Aggressive Lymphomas Acute and subacute bursitis Acute exacerbations of chronic obstructive pulmonary disease (COPD) Acute exacerbations of multiple sclerosis Acute gouty arthritis Acute leukemia Acute leukemia of childhood Acute nonspecific tenosynovitis Acute or chronic solid organ rejection Acute rheumatic carditis Aggressive lymphomas All indicated conditions (pediatric general dosing) Allergic Conditions (atopic dermatitis, drug hypersensitivity reactions, seasonal or perennial allergic rhinitis, serum sickness) Allergic States Allergic States (seasonal or perennial allergic rhinitis; asthma; contact dermatitis; atopic dermatitis; serum sickness; drug hypersensitivity reactions) Allergic States; Dermatologic Diseases; Endocrine Disorders; Gastrointestinal Diseases; Hematologic Disorders; Neoplastic Diseases; Ophthalmic Diseases; Respiratory Diseases; Rheumatic Disorders; Miscellaneous (general pediatric dosing) Allergic bronchopulmonary aspergillosis Allergic conditions (atopic dermatitis, drug hypersensitivity reactions, seasonal or perennial allergic rhinitis, serum sickness) Allergic conjunctivitis Allergic corneal marginal ulcers Ankylosing spondylitis Anterior segment inflammation Aspiration pneumonitis Asthma Asthma (allergic) Asthma (non-allergic) Asthma (pediatric) Asthma (pediatric, uncontrolled by inhaled corticosteroids and long-acting bronchodilators) Asthma uncontrolled by inhaled corticosteroids and long-acting bronchodilators Asthma — pediatric (uncontrolled by inhaled corticosteroids and long-acting bronchodilators) Atopic dermatitis Berylliosis Bronchial asthma Bullous dermatitis herpetiformis Cerebral edema associated with primary or metastatic brain tumor, craniotomy or head injury Chorioretinitis Congenital (erythroid) hypoplastic anemia Congenital adrenal hyperplasia Contact dermatitis Crohn's Disease Crohn's disease Dermatologic Diseases Dermatologic Diseases (pemphigus; bullous dermatitis herpetiformis; severe erythema multiforme; exfoliative erythroderma; mycosis fungoides) Dermatomyositis (polymyositis) Dermatomyositis/polymyositis Diamond-Blackfan anemia Diffuse posterior uveitis and choroiditis Drug hypersensitivity reactions Edematous States Edematous States (nephrotic syndrome) Edematous States (nephrotic syndrome) — adults Edematous States (nephrotic syndrome) — pediatric Endocrine Disorders Endocrine Disorders (adrenocortical insufficiency; congenital adrenal hyperplasia; hypercalcemia associated with cancer; nonsuppurative thyroiditis) Endocrine Disorders (primary or secondary adrenocortical insufficiency; congenital adrenal hyperplasia; hypercalcemia associated with cancer; nonsuppurative thyroiditis) Epicondylitis Erythroblastopenia (RBC anemia) Exfoliative dermatitis Exfoliative erythroderma Fulminating or disseminated pulmonary tuberculosis Gastrointestinal Diseases Gastrointestinal Diseases (ulcerative colitis; regional enteritis) General Pediatric Indications (all indicated conditions) General pediatric dosing (all non-asthma, non-nephrotic syndrome pediatric indications) General pediatric indications (all conditions) Hematologic Disorders Hematologic Disorders (idiopathic thrombocytopenic purpura; secondary thrombocytopenia; acquired hemolytic anemia; pure red cell aplasia; Diamond-Blackfan anemia) Hematologic Disorders (idiopathic thrombocytopenic purpura; secondary thrombocytopenia; autoimmune hemolytic anemia; pure red cell aplasia; Diamond-Blackfan anemia) Herpes zoster ophthalmicus Hypercalcemia associated with cancer Hypercalcemia of malignancy Hypersensitivity pneumonitis Idiopathic bronchiolitis obliterans with organizing pneumonia Idiopathic eosinophilic pneumonias Idiopathic nephrotic syndrome Idiopathic pulmonary fibrosis Idiopathic thrombocytopenic purpura Iritis and Iridocyclitis Iritis and iridocyclitis Juvenile rheumatoid arthritis Keratitis Leukemias and lymphomas Loeffler's syndrome Miscellaneous Miscellaneous (Tuberculous Meningitis, Trichinosis, Solid Organ Rejection) Miscellaneous (Tuberculous Meningitis; Trichinosis; Solid Organ Rejection) Miscellaneous (tuberculous meningitis, trichinosis, solid organ rejection) Miscellaneous (tuberculous meningitis; tuberculosis with enlarged mediastinal lymph nodes or pleural/pericardial effusion; trichinosis with neurologic or myocardial involvement; acute or chronic solid organ rejection) Miscellaneous (tuberculous meningitis; tuberculosis with enlarged mediastinal lymph nodes; tuberculosis with pleural or pericardial effusion; trichinosis with neurologic or myocardial involvement; acute or chronic solid organ rejection) Miscellaneous (tuberculous meningitis; tuberculosis with mediastinal lymph nodes; tuberculosis with pleural or pericardial effusion; Trichinosis with neurologic or myocardial involvement; acute or chronic solid organ rejection) Miscellaneous (tuberculous meningitis; tuberculosis with mediastinal lymph nodes; tuberculosis with pleural/pericardial effusion; trichinosis with neurologic/myocardial involvement; solid organ rejection) Miscellaneous (tuberculous meningitis; tuberculosis with mediastinal lymph nodes; tuberculosis with pleural/pericardial effusion; trichinosis; acute or chronic solid organ rejection) Multiple Sclerosis Multiple Sclerosis (acute exacerbations) Multiple conditions — pediatric general dosing Mycosis fungoides Neoplastic Diseases Neoplastic Diseases (acute leukemia and aggressive lymphomas) Neoplastic Diseases (acute leukemia; aggressive lymphomas) Nephrotic Syndrome Nephrotic syndrome Nonsuppurative thyroiditis Ophthalmic Diseases Ophthalmic Diseases (uveitis; ocular inflammatory conditions; temporal arteritis; sympathetic ophthalmia) Optic neuritis Pediatric (general — all non-nephrotic, non-asthma indications) Pediatric conditions (general) Pemphigus Pneumocystis carinii pneumonia (PCP) associated with hypoxemia in HIV-positive individuals Pneumocystis carinii pneumonia (PCP) associated with hypoxemia in HIV-positive patients Polymyalgia rheumatica Polymyalgia rheumatica/temporal arteritis Post-traumatic osteoarthritis Primary or secondary adrenocortical insufficiency Psoriatic arthritis Pure red cell aplasia Regional enteritis Relapsing polychondritis Respiratory Diseases Respiratory Diseases (sarcoidosis; eosinophilic pneumonias; pulmonary tuberculosis; asthma; hypersensitivity pneumonitis; idiopathic pulmonary fibrosis; COPD exacerbations; PCP with hypoxemia; allergic bronchopulmonary aspergillosis; bronchiolitis obliterans with organizing pneumonia) Respiratory Diseases (symptomatic sarcoidosis; idiopathic eosinophilic pneumonias; pulmonary tuberculosis; asthma; hypersensitivity pneumonitis; idiopathic pulmonary fibrosis; acute exacerbations of COPD; PCP with hypoxemia in HIV; allergic bronchopulmonary aspergillosis; idiopathic bronchiolitis obliterans with organizing pneumonia) Respiratory Diseases (symptomatic sarcoidosis; idiopathic eosinophilic pneumonias; pulmonary tuberculosis; asthma; hypersensitivity pneumonitis; idiopathic pulmonary fibrosis; acute exacerbations of COPD; Pneumocystis carinii pneumonia; allergic bronchopulmonary aspergillosis; idiopathic bronchiolitis obliterans with organizing pneumonia) Rheumatic Disorders Rheumatic Disorders (psoriatic arthritis; rheumatoid arthritis including juvenile rheumatoid arthritis; ankylosing spondylitis; acute and subacute bursitis; acute nonspecific tenosynovitis; acute gouty arthritis; epicondylitis; systemic lupus erythematosus; dermatomyositis; polymyalgia rheumatica; Sjogren's syndrome; relapsing polychondritis; vasculitis) Rheumatic Disorders (psoriatic arthritis; rheumatoid arthritis; juvenile rheumatoid arthritis; ankylosing spondylitis; acute and subacute bursitis; acute nonspecific tenosynovitis; acute gouty arthritis; epicondylitis; systemic lupus erythematosus; dermatomyositis; polymyalgia rheumatica; Sjogren's syndrome; relapsing polychondritis; vasculitis) Rheumatic Disorders (psoriatic arthritis; rheumatoid arthritis; juvenile rheumatoid arthritis; ankylosing spondylitis; bursitis; tenosynovitis; gouty arthritis; epicondylitis; systemic lupus erythematosus; dermatomyositis; polymyalgia rheumatica; Sjogren's syndrome; relapsing polychondritis; vasculitis) Rheumatoid arthritis Rheumatoid arthritis, including juvenile rheumatoid arthritis Seasonal or perennial allergic rhinitis Secondary thrombocytopenia Serum sickness Severe erythema multiforme (Stevens-Johnson syndrome) Severe psoriasis Severe seborrheic dermatitis Sjogren's syndrome Sympathetic ophthalmia Symptomatic sarcoidosis Synovitis of osteoarthritis Systemic dermatomyositis (polymyositis) Systemic lupus erythematosus Temporal arteritis Trichinosis with neurologic or myocardial involvement Tuberculosis with enlarged mediastinal lymph nodes causing respiratory difficulty Tuberculosis with pleural or pericardial effusion Tuberculous meningitis Tuberculous meningitis with subarachnoid block or impending block Ulcerative colitis Uveitis and ocular inflammatory conditions unresponsive to topical corticosteroids Vasculitis
No conditions match your search.
Drug Class
Corticosteroid Hormone Receptor Agonists [MoA]Corticosteroid [EPC]
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Frequently Asked Questions
Is there an available Prednisolone billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for PREDNISOLONE.
Are there any available Prednisolone patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for PREDNISOLONE.
Where can I find Prednisolone prescribing information?
PREDNISOLONE prescribing information can be found at the link below: Visit Here →
Where can I find Prednisolone side effect information?
Information regarding PREDNISOLONE's side effects can be found at MedlinePlus Visit Here →
Does billing PREDNISOLONE require JZ/JW wastage modifiers?
CMS does not include PREDNISOLONE (J7510) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7510. For more information, visit the link below.
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