Enoby Q Code: Q5167

Drug & Product Overview

HCPCS Descriptor Injection, denosumab-qbde (enoby/xtrenbo), biosimilar, 1 mg

HCPCS Added Date July 1, 2026

Manufacturer Hikma

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection

About Enoby

Enoby is a medication aligned to the HCPCS Q Code: Q5167 for billing, pricing, and reimbursement purposes in the United States. Classified under Osteoporosis, it is administered via the subcutaneous route and manufactured by Hikma.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9165-01	Enoby	Hikma Pharmaceuticals USA Inc.	60	60 MG / 1 ML
00143-9166-01	Xtrenbo	Hikma Pharmaceuticals USA Inc.	120	120 MG / 1.7 ML

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Enoby Pricing & Reimbursement

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Denosumab Biosimilar Information:

Enoby Approval Date: September 26, 2025

Product Name	HCPCS Code	Active Ingredient	BLA Type
Prolia	J0897	Denosumab	351(a) Originator Product
Jubbonti and Wyost	Q5136	Denosumab	351(k) Interchangeable
Ospomyv and Xbryk	Q5159	Denosumab	351(k) Interchangeable
Stoboclo and Osenvelt	Q5157	Denosumab	351(k) Interchangeable
Bomyntra and Conexxence	Q5158	Denosumab	351(k) Interchangeable
Bildyos and Bilprevda	Q5162	Denosumab	351(k) Interchangeable
Aukelso and Bosaya	Q5161	Denosumab	351(k) Interchangeable
Enoby and Xtrenbo	Q5167	Denosumab	351(k) Interchangeable
Osvyrti and Jubereq	Q5166	Denosumab	351(k) Interchangeable
Oziltus	Q5165	Denosumab	351(k) Interchangeable
Boncresa	Q5171	Denosumab	351(k) Interchangeable
Ponlimsi	Q5173	Denosumab	351(k) Interchangeable

One of 11 Prolia/Xgeva biosimilars FDA-approved since 2024 See each approval by month on the BuyandBill.com Pipeline calendar. Comes with Pro. Every denosumab approval, month by month.

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Enoby CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

Enoby Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Bone loss receiving adjuvant aromatase inhibitor therapy for breast cancer Bone loss receiving androgen deprivation therapy for nonmetastatic prostate cancer Giant cell tumor of bone Glucocorticoid-induced osteoporosis Hypercalcemia of malignancy Multiple myeloma and bone metastases from solid tumors Osteoporosis Osteoporosis at high risk for fracture

Drug Class

RANK Ligand Blocking Activity [MoA]RANK Ligand Inhibitor [EPC]

Frequently Asked Questions

Is there an available Enoby billing and coding guide?

A manufacturer-published billing and coding guide for ENOBY was not found.

Are there any available Enoby patient assistance programs?

No manufacturer-published ENOBY patient assistance link was found.

Where can I find Enoby prescribing information?

ENOBY prescribing information can be found at the link below: Visit Here →

Where can I find Enoby side effect information?

Information regarding ENOBY's side effects can be found at MedlinePlus Visit Here →

Does billing ENOBY require JZ/JW wastage modifiers?

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers.

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