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Updated July 1st, 2026

LUPRON DEPOT J Code: J1950

Injection, leuprolide acetate (for depot suspension), per 3.75 mg

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Q4 2026 Medicare Payment Limit for J1950, effective October 1, 2026: $1,799.052 per HCPCS billing unit, down 2.3% from $1,841.261. From CMS's final file.

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Medicare Payment Limit ?
$1,841.261
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$1,841.261
/ HCPCS billing unit · APC 0800
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
8
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Drug & Product Overview

HCPCS Descriptor Injection, leuprolide acetate (for depot suspension), per 3.75 mg
HCPCS Added Date January 1, 1986
Manufacturer Multiple Manufacturers
Route of Administration Intramuscular
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Kit

About LUPRON DEPOT

Lupron Depot is a medication aligned to the HCPCS J Code: J1950 for billing, pricing, and reimbursement purposes in the United States. This Growth Disorder medication is administered via the intramuscular route and manufactured by multiple companies.

According to CMS Drug Use Information: Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 8 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00074-2108-03 Lupron Depot-PED AbbVie Inc. 2 Kit
00074-2282-03 Lupron Depot-PED AbbVie Inc. 3 Kit
00074-2440-03 Lupron Depot-PED AbbVie Inc. 4 Kit
00074-3575-01 Lupron Depot-PED AbbVie Inc. 12 Kit
00074-3641-03 Lupron Depot AbbVie Inc. 1 Kit
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LUPRON DEPOT Pricing & Reimbursement

J1950 Private Payer Reimbursement
$1,813.58 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Leuprolide Acetate 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J1950 Abbvie Leuprolide Acetate Injection, leuprolide acetate (for depot suspension), per 3.75 mg
J1951 Tolmar Pharmaceuticals, Inc Leuprolide Acetate Injection, leuprolide acetate for depot suspension (fensolvi), 0.25 mg
J1952 Accord Leuprolide Acetate Leuprolide injectable, camcevi, 1 mg
J1954 Generic Code (Multiple Manufacturers) Leuprolide Acetate Injection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mg
J9217 Generic Code (Multiple Manufacturers) Leuprolide Acetate Leuprolide acetate (for depot suspension), 7.5 mg

LUPRON DEPOT CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96402 Chemotherapy administration, subcutaneous or intramuscular; hormonal anti-neoplastic
Not on the CMS JW / JZ list

CMS does not include Lupron Depot (J1950) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1950. Wastage billing guide →

LUPRON DEPOT Medically Unlikely Edits (MUE)

The most billing units of J1950 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 3.75 mg.

Practitioner Office & Hospital Outpatient
12 units / day
= 45 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

LUPRON DEPOT Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Central Precocious Puberty Endometriosis Uterine Leiomyomata (Fibroids)

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Frequently Asked Questions

Is there an available Lupron Depot billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for LUPRON DEPOT.
Are there any available Lupron Depot patient assistance programs?
LUPRON DEPOT patient assistance information can be found through Abbvie. Visit Here →
Where can I find Lupron Depot prescribing information?
LUPRON DEPOT prescribing information can be found at the link below: Visit Here →
Where can I find Lupron Depot side effect information?
Information regarding LUPRON DEPOT's side effects can be found at MedlinePlus Visit Here →
Does billing LUPRON DEPOT require JZ/JW wastage modifiers?
CMS does not include LUPRON DEPOT (J1950) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1950. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to LUPRON DEPOT.

J1951FENSOLVIInjection, leuprolide acetate for depot suspension (fensolvi), 0.25 mgTolmar Pharmaceuticals, IncAdded July 1, 2021J9217ELIGARDLeuprolide acetate (for depot suspension), 7.5 mgMultiple ManufacturersAdded January 1, 1991J1954Lutrate DepotInjection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mgAvyxa PharmaAdded January 1, 2023J9218LEUPROLIDE ACETATELeuprolide acetate, per 1 mgMultiple ManufacturersAdded January 1, 1990J9202ZOLADEXGoserelin acetate implant, per 3.6 mgMultiple ManufacturersAdded January 1, 1991J0834CORTROSYNInjection, cosyntropin, 0.25 mgMultiple ManufacturersAdded January 1, 2010J1930SOMATULINE DEPOTInjection, lanreotide, 1 mgMultiple ManufacturersAdded January 1, 2009J2170INCRELEXInjection, mecasermin, 1 mgEton PharmaceuticalsAdded January 1, 2007J2353SANDOSTATIN LAR DEPOTInjection, octreotide, depot form for intramuscular injection, 1 mgMultiple ManufacturersAdded January 1, 2004J2354OCTREOTIDE ACETATEInjection, octreotide, non-depot form for subcutaneous or intravenous injection, 25 mcgMultiple ManufacturersAdded January 1, 2004