LEUPROLIDE ACETATE J Code: J9218

Self-Administered Drug Exclusion 7 Medicare Administrative Contractors list J9218 as usually self-administered and exclude it from Part B coverage in their jurisdictions. Check the article for your MAC before billing: CGS, First Coast, Noridian (A53032), Noridian (A53033), Novitas, Palmetto, Wellpoint Federal, WPS · All SAD lists →

Drug & Product Overview

HCPCS Descriptor Leuprolide acetate, per 1 mg

HCPCS Added Date January 1, 1990

Manufacturer Multiple Manufacturers

Route of Administration Subcutaneous

Generic Status Multi-Source; Generic

Dosage Type Multi-Dose

Dosage Form Kit

About LEUPROLIDE ACETATE

Leuprolide Acetate is a medication aligned to the HCPCS J Code: J9218 for billing, pricing, and reimbursement purposes in the United States. Classified under Oncology, it is administered via the subcutaneous route and manufactured by multiple companies.

Manufacturers, reach out to us to add more information.

NDC Code Information

8 NDC packages are crosswalked to J9218. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	LEUPROLIDE ACETATE
	LEUPROLIDE ACETATE
	LEUPROLIDE ACETATE
	LEUPROLIDE ACETATE

Login to view 8 NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

LEUPROLIDE ACETATE Pricing & Reimbursement

J9218 Private Payer Reimbursement

$52.24 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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LEUPROLIDE ACETATE CPT Administration Codes

CPT Code	Description
96402	Chemotherapy administration, subcutaneous or intramuscular; hormonal anti-neoplastic

Not on the CMS JW / JZ list

CMS does not include Leuprolide Acetate (J9218) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9218. Wastage billing guide →

LEUPROLIDE ACETATE Medically Unlikely Edits (MUE)

The most billing units of J9218 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

1 unit / day

= 1 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

LEUPROLIDE ACETATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Advanced Prostatic Cancer Advanced prostatic cancer

Frequently Asked Questions

Is there an available Leuprolide Acetate billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for LEUPROLIDE ACETATE.

Are there any available Leuprolide Acetate patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for LEUPROLIDE ACETATE.

Where can I find Leuprolide Acetate prescribing information?

LEUPROLIDE ACETATE prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Leuprolide Acetate side effect information?

Our team has not yet identified a source of side effects information for LEUPROLIDE ACETATE. Please check back in a few weeks.

Does billing LEUPROLIDE ACETATE require JZ/JW wastage modifiers?

CMS does not include LEUPROLIDE ACETATE (J9218) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9218. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.